The first episode of this CMEO BriefCase series focuses on a patient case that requires differentiating ARIA from other conditions with a similar presentation in the emergency care setting, highlighting ARIA-related symptoms, listing other clinical manifestations of ARIA as described in clinical trials, and reviewing contraindicated medications for patients receiving an ATT.
Nicolas Villain, MD, PhD, is a tenured Associate Professor of Neurology at Sorbonne University, Paris, France and a cognitive and behavioral neurologist at the Institute of Memory and Alzheimer’s Disease, Department of Neurology, Pitié-Salpêtrière Hospital, Paris. He trained as an MD and a clinical fellow in Paris in Prof. Bruno Dubois’ group and carried out his PhD with Dr. Gaël Chételat in Caen, France, where he worked on multimodal neuroimaging and disconnection mechanisms in Alzheimer’s disease. He currently leads projects on brain network vulnerability using multimodal neuroimaging and on fluid biomarkers of Alzheimer’s disease in Prof. Kaj Blennow’s new group at the Paris Brain Institute.
Shared decision-making (SDM) is a collaborative effort between patients and clinicians to share evidence and consider options regarding health care decisions. SDM is a significant facet of chronic kidney disease (CKD) care and is especially relevant for anemia in CKD, wherein treatment options carry uncertainty and variability. Patients, however, lack knowledge of anemia in CKD; many patients are not aware of their hemoglobin levels or recognize that their anemia and kidney disease are linked, and only half understand different treatment options. It is imperative that clinicians are appraised of how to educate CKD patients with anemia and facilitate informed care decisions, especially in the sensitive contexts of life experience and culture for underserved and rural populations.
In the third activity of this CME Outfitters BriefCase series, expert faculty utilize case-based learning to guide learners on integration of SDM principles to ensure that patient needs and preferences are aligned with anemia and CKD treatment plans.
Bruce Spinowitz, MD, is a practicing nephrologist in Queens, New York. He is vice chairman of the Department of Medicine and associate director of the Renal Division at New York-Presbyterian Queens in Flushing as well as a professor of clinical medicine at Weill Medical College of Cornell University in New York City. Dr. Spinowitz graduated from New York University School of Medicine in 1973. He completed an internship and residency in internal medicine at Bellevue Hospital in New York City. Dr. Spinowitz was a National Institutes of Health (NIH) postdoctoral fellow in physiology and completed a second fellowship in nephrology at New York University School of Medicine. He is board-certified in internal medicine and nephrology.
Dr. Spinowitz’s research areas of interest include diabetic nephropathy, anemia, lupus nephritis, secondary hypoparathyroidism, peritoneal dialysis, and new therapies for hyperkalemia. He is a member of the National Kidney Foundation Medical Advisory Board. Dr. Spinowitz has published more than 60 original research articles in peer-reviewed journals. He has more than 80 abstracts and posters presented nationally and internationally at the annual meetings of the International Society of Nephrology (ISN), the American Society for Artificial Internal Organs (ASAIO), the American Society of Nephrology (ASN), the International Society of Peritoneal Dialysis (ISPD), the American Diabetes Association, and the American College of Clinical Pharmacy (ACCP).
Dr. Spinowitz is a fellow of the American College of Physicians and a member of the ASN, ISN, ISPD, and Renal Physicians Association. Since 2001, he has been a Castle Connolly “Top Doctor” and was awarded Nephrologist of the Year by the American Kidney Foundation in 2014.
Charles Vega, MD grew up in Northern California and completed his undergraduate degree at Harvard University. He attended medical school at the University of Wisconsin Madison and completed residency training in Family Medicine at University of California Irvine (UCI). He remained as faculty in the Department of Family Medicine at UCI and now holds the title of Health Sciences Clinical Professor. He is the Executive Director of UCI’s Program in Medical Education for the Latino Community and won a Macy Faculty Scholarship to improve patient-centered health education at UCI. He currently serves as Assistant Dean for Culture and Community Education in the UCI School of Medicine.
Dr. Vega has seen patients and taught medical students and residents at UCI Health Family Health Center, Santa Ana for the past 20 years. This clinic is a federally qualified health center and the largest safety-net clinic for Orange County. Dr. Vega’s academic interests are focused on access to quality, compassionate medical care for underserved populations, and the development of training programs to promote this vision of healthcare.
Monica Peek, MD, MPH, MSc is an Ellen H. Block Professor of Health Justice in the Department of Medicine. She is also the Associate Director, Chicago Center for Diabetes Translation Research, and Director of Research, MacLean Center for Clinical Medical Ethics. She is a practicing internist, medical educator, and clinician investigator. Her research pursues health equity and social justice, with a focus on promoting equitable doctor/patient relationships among racial minorities, integrating the medical and social needs of patients, and addressing health care discrimination and structural racism impacting health outcomes (e.g., diabetes, COVID-19). Dr. Peek has authored more than 200 peer-reviewed publications and abstracts on health care disparities, diversity, and bias; has been the principal investigator of multiple grants to address health disparities; and has been invited to speak at numerous local and national medical meetings.
The third and final episode of this CMEO BriefCase series focuses on a case involving a patient on an ATT presenting to the emergency department (ED), highlighting ED protocols to streamline care for patients with severe ARIA, recommendations for treatment and supportive care measures, global resources for guidance as the ATT landscape expands, management of ARIA according to best guidance, and communication with ATT-treating clinicians and radiologists.
Karen Greenberg, DO, FACOEP-D, FAAEM, FAHA is double board certified in emergency medicine and neurocritical care and highly specialized in the treatment of neurological emergencies.
Dr. Greenberg’s work was critical to the establishment of the nation’s first dedicated Neurologic Emergency Department. The American College of Osteopathic Emergency Physicians (ACOEP) recognized her innovations to speed critical treatment to patients experiencing acute ischemic stroke and awarded her its inaugural Practice Innovation Award. In 2021 Dr. Greenberg received the Willoughby Award from the ACOEP that honors the top female leader in emergency medicine.
Dr Greenberg has numerous publications in emergency, neurology, and neurosurgery journals and has authored book chapters as well. She has been honored with distinguished fellowship of the American College of Osteopathic Emergency Physicians, and is a fellow of the American Academy of Emergency Medicine and American Heart Association as well. She is an assistant professor of neurosurgery, neurology, and emergency medicine with Drexel University College of Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia College of Osteopathic Medicine, and Rowan School of Osteopathic Medicine.
Nicolas Villain, MD, PhD, is a tenured Associate Professor of Neurology at Sorbonne University, Paris, France and a cognitive and behavioral neurologist at the Institute of Memory and Alzheimer’s Disease, Department of Neurology, Pitié-Salpêtrière Hospital, Paris. He trained as an MD and a clinical fellow in Paris in Prof. Bruno Dubois’ group and carried out his PhD with Dr. Gaël Chételat in Caen, France, where he worked on multimodal neuroimaging and disconnection mechanisms in Alzheimer’s disease. He currently leads projects on brain network vulnerability using multimodal neuroimaging and on fluid biomarkers of Alzheimer’s disease in Prof. Kaj Blennow’s new group at the Paris Brain Institute.
The second episode of this CMEO BriefCase series focuses on a patient case that demonstrates real-world challenges such as obtainment of an accurate medical history, imaging needs and interpretations, and what to do if magnetic resonance imaging (MRI) is not accessible.
Nicolas Villain, MD, PhD, is a tenured Associate Professor of Neurology at Sorbonne University, Paris, France and a cognitive and behavioral neurologist at the Institute of Memory and Alzheimer’s Disease, Department of Neurology, Pitié-Salpêtrière Hospital, Paris. He trained as an MD and a clinical fellow in Paris in Prof. Bruno Dubois’ group and carried out his PhD with Dr. Gaël Chételat in Caen, France, where he worked on multimodal neuroimaging and disconnection mechanisms in Alzheimer’s disease. He currently leads projects on brain network vulnerability using multimodal neuroimaging and on fluid biomarkers of Alzheimer’s disease in Prof. Kaj Blennow’s new group at the Paris Brain Institute.
Jimmy L. Pruitt III, PharmD, BCPS, BCCCP, BCEMP, is originally from Orlando, Florida, and received his Doctor of Pharmacy from Presbyterian College School of Pharmacy in 2017. He completed a PGY-1 pharmacy residency at Florida Hospital Orlando and then went on to Grady Health System in Atlanta, Georgia, for his PGY2 emergency medicine residency. Dr. Pruitt is currently an emergency medicine clinical pharmacy specialist at the Medical University of South Carolina (MUSC) in Charleston, South Carolina. He was awarded Grady Pharmacist of the Year in 2019 as a PGY2 emergency medicine resident, which was a first in the program’s 30+ year history. In 2020, he obtained Board-Certified Pharmacotherapy Specialist (BCPS) and Board-Certified Critical Care Pharmacist (BCCCP) recognition. Also, in 2020, he won the Society of Academic Emergency Medicine (SAEM) Got Talent competition for his educational series “Pharmacy Friday Pearls,” which was the first time a pharmacist won the event. In 2021, Dr. Pruitt was honored with the Excellence in Diversity award from MUSC College of Pharmacy, was Presbyterian College School of Pharmacy (PCSP) Alumni of the Year, and was keynote speaker for the 2021 PCPS graduation. His professional interests include cardiac arrest, shock syndromes, trauma, and hosting his podcast Pharm So Hard. Dr. Pruitt obtained board certification in emergency medicine in May 2023.
Though the overall prevalence of major depressive disorder (MDD) is estimated to be largely equivalent across racial/ethnic groups, there is a significant disparity in the rate of diagnosis of MDD for many racial/ethnic underserved communities, including Black and Hispanic groups. In addition, amongst those from these communities who do receive a diagnosis, treatment offerings are often limited, with antidepressant therapy as well as psychotherapy offered at lower rates as compared to their non-Hispanic White counterparts. Social determinants / drivers of health play an additional role in these disparate outcomes, as negative drivers of health have been associated with progression to treatment resistant depression (TRD). It is imperative that each member of the multidisciplinary care team works together to address these disparities in order to improve equity in treatment and outcomes for all patients.
In this CMEO BriefCase, expert faculty will utilize case-based learning to illustrate these pervasive disparities through the stories of two patients, Luna and Eralia, while offering strategies to address inequities in the treatment and outcomes of patients with MDD and/or TRD.
Rakesh Jain, MD, MPH, is a Clinical Professor in the department of Psychiatry at the Texas Tech Health Sciences Center School of Medicine – Permian Basin in Midland, Texas and in private practice in Austin, Texas. Dr. Jain attended medical school at the University of Calcutta in India. He received his Master of Public Health (MPH) degree from the University of Texas School of Public Health in Houston, where he was awarded a National Institute/Center for Disease Control Competitive Traineeship. His research thesis focused on the impact of substance abuse.
Dr. Jain completed his residency in psychiatry at the Department of Psychiatry and Behavioral Sciences at the University of Texas Medical School at Houston. He then completed a postdoctoral fellowship in research psychiatry at the University of Texas Mental Sciences Institute in Houston. He was awarded the National Research Service Award in support of his postdoctoral fellowship.
Dr. Jain has been involved in over 100 research projects studying the effects of medications on short-term and long-term treatment of depression, anxiety, pain/mood overlap disorders, ADHD, and psychosis in adult and child/adolescent populations. He has presented at the World Psychiatric Congress held in Prague, and at Depression and Pain Forum meetings internationally. He is the author of 55 articles published in various journals and magazines, such as the Journal of Psychiatric Research and Journal of Clinical Psychiatry, among others, and has presented over 25 original research posters at meetings such as the American Psychological Association (APA), the American College of Neuropsychopharmacology (ACNP), the American Academy of Child and Adolescent Psychiatry (AACAP), the U.S. Psychiatric Congress, and more. He has co-authored six books that range from patient education to cutting-edge neurobiologic findings in psychiatry and mental health. He serves on several advisory boards focusing on drug development and disease state education. He was also recently the Chair of the U.S. Psychiatric Congress, and for several years, has served as a member of the Steering Committee for U.S. Psychiatric Annual Congress. He is a recipient of the Public Citizen of the Year award from the National Association of Social Workers, Gulf Coast Chapter, in recognition of his community and peer education, and championing of mental health issues.
Monica Peek, MD, MPH, MSc is an Ellen H. Block Professor of Health Justice in the Department of Medicine. She is also the Associate Director, Chicago Center for Diabetes Translation Research, and Director of Research, MacLean Center for Clinical Medical Ethics. She is a practicing internist, medical educator, and clinician investigator. Her research pursues health equity and social justice, with a focus on promoting equitable doctor/patient relationships among racial minorities, integrating the medical and social needs of patients, and addressing health care discrimination and structural racism impacting health outcomes (e.g., diabetes, COVID-19). Dr. Peek has authored more than 200 peer-reviewed publications and abstracts on health care disparities, diversity, and bias; has been the principal investigator of multiple grants to address health disparities; and has been invited to speak at numerous local and national medical meetings.