Blog Category: On-Demand

From Biomarkers to Bedside: Translating IIM Classification into Targeted Treatment Strategies

The idiopathic inflammatory myopathy (IIM) landscape is evolving rapidly, transforming how clinicians recognize disease, assess risk, and select treatment, but translating these advances into everyday practice remains a challenge. As biomarkers and myositis-specific autoantibodies enable increasingly precise subtype classification, clinicians …

Individualizing HIV Treatment for Diverse Populations

Although advances in antiretroviral therapy (ART) have transformed human immunodeficiency virus (HIV) into a manageable chronic condition, important gaps persist in the consistent, equitable application of care across diverse populations and global settings. Rapid innovation—including long-acting injectable (LAI) and multi-mechanism …

Integrating Clinical Trial Evidence into Global HIV Practice

Despite significant advances in human immunodeficiency virus (HIV) care, there are persistent gaps in translating clinical trial evidence into real-world practice, limiting optimal outcomes. Clinicians must keep pace with a rapidly evolving treatment landscape—including antiretroviral therapy (ART) such as long-acting …

Implementation and Access in Global HIV Care

While treatment innovations have significantly improved outcomes for individuals with human immunodeficiency virus (HIV), gaps persist in the consistent delivery of equitable, guideline-concordant care, particularly among diverse and underserved populations. Optimal use of therapies, including long-acting injectables (LAIs), is restricted …

Global Guidelines and Strategies for HIV Screening and Diagnosis

Despite major advances in human immunodeficiency virus (HIV) management—including effective antiretroviral therapy (ART) and long-acting injectables—gaps in screening, testing, and diagnosis continue to limit patient outcomes and prevention efforts. Many clinicians, particularly in primary care and community settings, face challenges …

Beyond the Bowel: Addressing Obesity as a Modifiable Driver of IBD Outcomes

Obesity is transforming the landscape of inflammatory bowel disease (IBD), shaping disease activity, treatment response, and long-term prognosis. As evidence reveals the impact of excess weight on biologic and JAK inhibitor effectiveness, emerging anti-obesity therapies, including GLP-1 receptor agonists, are …

Beyond VEGF: Understanding Blood-Retinal Barrier Biology and Emerging Mechanisms in DME and Neovascular AMD

Anti-vascular endothelial growth factor (anti-VEGF) therapy transformed the management of diabetic macular edema (DME) and neovascular age-related macular degeneration (nAMD), but it has not solved either disease. Roughly 40% to 60% of patients with DME and 40% to 50% with …

Beyond the Bowel: An Interactive Simulation on Obesity as a Modifiable Driver of IBD Outcomes

Obesity is transforming the landscape of inflammatory bowel disease (IBD), shaping disease activity, treatment response, and long-term prognosis. As evidence reveals the impact of excess weight on biologic and JAK inhibitor effectiveness, emerging anti-obesity therapies, including GLP-1 receptor agonists, are …

The MG You’re Missing: Recognizing and Managing MuSK+, LRP4+, and Triple-Seronegative Myasthenia Gravis

Despite advances in generalized myasthenia gravis (gMG), muscle-specific tyrosine kinase (MuSK+), low density lipoprotein receptor related protein 4 (LRP4+), and triple-seronegative MG remain underrecognized and are often managed using paradigms derived from acetylcholine receptor (AChR)-positive disease. Neurologists, neuromuscular specialists, nurse …