In this CME Outfitters Snack, expert faculty will discuss biomarker research findings presented at the Clinical Trials on Alzheimer’s Disease (CTAD) conference, review the identification and measurement of AD pathophysiology, examine a framework for evidencing biomarker profiles of AD, provide updates on prognostic performance and interpretation of biomarkers, and conduct a case-based discussion of clinical impacts and applications.
0.5
11/30/2023
Michelle M. Mielke
Michelle M. Mielke, PhD, is Chair of the Department of Epidemiology and Prevention, Professor of Epidemiology, and Professor of Gerontology and Geriatric Medicine at Wake Forest University School of Medicine. She works as a translational epidemiologist to further understand the etiology and epidemiology of neurodegenerative diseases.
Michelle M. Mielke
Michelle M. Mielke, PhD, is Chair of the Department of Epidemiology and Prevention, Professor of Epidemiology, and Professor of Gerontology and Geriatric Medicine at Wake Forest University School of Medicine. She works as a translational epidemiologist to further understand the etiology and epidemiology of neurodegenerative diseases. One focus of her research is understanding the utility of blood-based biomarkers for implementation at the population level for screening and diagnosing Alzheimer’s disease and related dementias. Another focus of Dr. Mielke’s research is on understanding sex and gender differences in the development and progression of Alzheimer’s disease and related dementias. She is principal investigator of several National Institutes of Health (NIH)-funded clinical and epidemiological-based grants and has published over 400 manuscripts. Dr. Mielke received the John R. Raymond Mentor Award from the Women Scholars Initiative and recently became a Fellow in the American Association for the Advancement of Science (AAAS), Section on Neuroscience.
Anna D. Burke
Anna D. Burke, MD, is a board-certified geriatric psychiatrist, the Karsten Solheim Chair for Dementia, and the Director of the Alzheimer’s and Memory Disorders Division at Barrow Neurological Institute in Phoenix, Arizona.
Anna D. Burke
Anna D. Burke, MD, is a board-certified geriatric psychiatrist, the Karsten Solheim Chair for Dementia, and the Director of the Alzheimer’s and Memory Disorders Division at Barrow Neurological Institute in Phoenix, Arizona. She also currently directs the Department of Neuropsychiatry at Barrow Neurological Institute. Barrow Neurological Institute is a world-class neurological and neurosurgical institute with a mission to accept challenges, reject norms, and push boundaries. The Barrow Alzheimer’s and Memory Disorders Division is one of the leading clinical and research institutes in the world, championing research in neurodegenerative disorders.
Dr. Burke has worked extensively with patients and families suffering with neurodegenerative disorders including Alzheimer’s disease (AD). Her area of expertise includes the diagnosis and management of cognitive disorders and the treatment of challenging behavioral and psychiatric disturbances that result from neurological conditions. In addition to her clinical work, she has led the development of comprehensive multispecialty clinical care models focused on improving the quality of care for individuals with cognitive impairment as well as improving the diagnosis and management of AD and related dementias in the community. Dr. Burke is a well-respected researcher, having led over 100 clinical trials of investigational therapies for AD and related dementias, and is a well-respected author and key opinion leader in the field.
In the first episode of this CMEOCast podcast series, Dr. Faulk and Dr. Renew will help learners to translate data into clinical practice regarding the differences between clinical assessment, qualitative assessment, and quantitative TOF monitoring and their efficacy in detecting residual neuromuscular blockade.
0.75
08/31/2023
Debra J. Faulk
Dr. Debra Faulk is an associate professor of pediatric anesthesiology and board-certified pediatric anesthesiologist. Her interests include sedation, simulation, pre-operative anxiety, and emergence agitation in kids.
Debra J. Faulk
Dr. Debra Faulk is an associate professor of pediatric anesthesiology and board-certified pediatric anesthesiologist. Her interests include sedation, simulation, pre-operative anxiety, and emergence agitation in kids. Dr. Faulk’s current research is in the monitoring of neuromuscular blockade in pediatric anesthesia, including studies looking a residual neuromuscular blockade as well as validation of objective EMG monitoring and their use for appropriate dosing of sugammadex in children.
J. Ross Renew
Ross Renew, MD, FASA, FASE, graduated from Clemson University (Chemistry, BS) and completed medical school at the University of South Carolina School of Medicine. Dr. Renew completed anesthesia residency at Mayo Clinic Florida and his fellowship in adult cardiothoracic anesthesiology at Mayo Clinic in Rochester, MN.
J. Ross Renew
Ross Renew, MD, FASA, FASE, graduated from Clemson University (Chemistry, BS) and completed medical school at the University of South Carolina School of Medicine. Dr. Renew completed anesthesia residency at Mayo Clinic Florida and his fellowship in adult cardiothoracic anesthesiology at Mayo Clinic in Rochester, MN. Dr. Renew then returned to Jacksonville and has worked on staff at Mayo Clinic Florida, where he is currently an Associate Professor of Anesthesiology. Dr. Renew serves as the Vice Chair of Research and Associate Program Director for the department’s residency program. His research interests involve neuromuscular blockade and monitoring, transesophageal echocardiography, and caring for the cardiac patient undergoing non-cardiac surgery.
In the second episode of the CMEOCast podcast series, J.Ross Renew, MD and Dru Riddle, DNP, CRNA will guide learners through strategies to best incorporate recommendations from the 2023 ASA guidelines into clinical practice.
0.75
09/26/2023
Dru Riddle
Dru is an academic and clinically-practicing Certified Registered Nurse Anesthetist (CRNA) and American Association of Nurse Anesthesiology (AANA) President. He also serves as co-chair of the Cochrane US Network.
Dru Riddle
Dru is an academic and clinically-practicing Certified Registered Nurse Anesthetist (CRNA) and American Association of Nurse Anesthesiology (AANA) President. He also serves as co-chair of the Cochrane US Network.
J. Ross Renew
Ross Renew, MD, FASA, FASE, graduated from Clemson University (Chemistry, BS) and completed medical school at the University of South Carolina School of Medicine. Dr. Renew completed anesthesia residency at Mayo Clinic Florida and his fellowship in adult cardiothoracic anesthesiology at Mayo Clinic in Rochester, MN.
J. Ross Renew
Ross Renew, MD, FASA, FASE, graduated from Clemson University (Chemistry, BS) and completed medical school at the University of South Carolina School of Medicine. Dr. Renew completed anesthesia residency at Mayo Clinic Florida and his fellowship in adult cardiothoracic anesthesiology at Mayo Clinic in Rochester, MN. Dr. Renew then returned to Jacksonville and has worked on staff at Mayo Clinic Florida, where he is currently an Associate Professor of Anesthesiology. Dr. Renew serves as the Vice Chair of Research and Associate Program Director for the department’s residency program. His research interests involve neuromuscular blockade and monitoring, transesophageal echocardiography, and caring for the cardiac patient undergoing non-cardiac surgery.
During this 60-minute recorded symposium, expert panelists will discuss GD, including its less commonly reported manifestations, diagnostic pathways, and patient-centric multidisciplinary management of the disorder.
1.0
03/07/2023
Neal J. Weinreb
Neal J. Weinreb, MD, FACP is a graduate of the Jewish Theological Seminary (Bachelor of Hebrew Literature), and SUNY Downstate Health Sciences University (MD, summa cum laude).
Neal J. Weinreb
Neal J. Weinreb, MD, FACP is a graduate of the Jewish Theological Seminary (Bachelor of Hebrew Literature), and SUNY Downstate Health Sciences University (MD, summa cum laude). After a residency in Internal Medicine at Albert Einstein College of Medicine and a fellowship and faculty position at Mt. Sinai School of Medicine, NY, he practiced Hematology and Medical Oncology in South Florida. Dr. Weinreb, the director of the University Research Foundation for Lysosomal Storage Diseases in Boca Raton, FL, retired from clinical practice in May 2018. He now devotes his entire professional attention to clinical research about Gaucher Disease and Fabry Disease. Dr Weinreb is a Voluntary Associate Professor of Human Genetics and Medicine at the University of Miami Miller School of Medicine. Dr. Weinreb is an investigator for the Gaucher and Fabry Registries and a member of the Medical Advisory Board for the National Gaucher Foundation and of the International Working Group for Gaucher Disease.
Coy Heldermon
Dr. Coy Heldermon is an associate professor of medicine and board-certified medical oncologist at the University of Florida with expertise in the treatment of breast cancer.
Coy Heldermon
Dr. Coy Heldermon is an associate professor of medicine and board-certified medical oncologist at the University of Florida with expertise in the treatment of breast cancer. He is a member of the American Society of Hematology and the American Society of Clinical Oncology. His research expertise is in the use of gene replacement and stem cell therapies for the treatment of inherited disorders such as lysosomal storage diseases.
Tamanna Roshan Lal
Dr. Roshan Lal is a Pediatric Clinical and Metabolic Geneticist working at the Rare Disease Institute, Children's National Hospital in Washington DC.
Tamanna Roshan Lal
Dr. Roshan Lal is a Pediatric Clinical and Metabolic Geneticist working at the Rare Disease Institute, Children’s National Hospital in Washington DC. Her clinical and research interests are geared towards improving the quality of life for children with rare genetic diseases, specifically lysosomal storage diseases and neuro-genetic disorders. Her special interest includes being involved in clinical trials using orphan drugs as well as gene therapy. She is currently the Director of Clinical Trials and Director of International Patient Consultations and Care Referrals for the Rare Disease Institute at the Children’s Hospital.
The first episode of this CMEO BriefCase series on narcolepsy focuses on screening for narcolepsy based on patient presentation, description of function, and changes in QoL to facilitate initiation of a treatment plan to optimize patient outcomes.
0.5
09/01/2023
Paul P. Doghramji
Paul P. Doghramji, MD, FAAFP, is a Senior Family Physician with Collegeville Family Practice and Medical Director of Health Services for Ursinus College in Collegeville, Pennsylvania.
Paul P. Doghramji
Paul P. Doghramji, MD, FAAFP, is a Senior Family Physician with Collegeville Family Practice and Medical Director of Health Services for Ursinus College in Collegeville, Pennsylvania. Dr. Doghramji earned his medical degree from Jefferson Medical College in Philadelphia, Pennsylvania and completed residency in Family Practice at Chestnut Hill Hospital. He is a member of the American Academy of Family Physicians (AAFP) and was awarded the AAFP Fellowship Degree in 2005. He is a member of the Pennsylvania Academy of Family Physicians. Dr Doghramji has been the recipient of the American Medical Association’s Physician Recognition Award in every qualifying year for 8 years. He has extensively published his research in peer-reviewed journals such as the American Journal of Medicine, Current Medical Research and Opinion, and Postgraduate Medicine. He has authored articles for numerous websites on topics such as sleep disorders, gout, rheumatoid arthritis (RA), biology of leg disorders, depression, chronic pain, health literacy, and diabetes. He is a co-author of the textbook Clinical Management of Insomnia, now in its second edition.
Richard K. Bogan
Dr. Bogan is the President of Bogan Sleep Consultants, LLC. He is also Associate Clinical Professor at the University of South Carolina School of Medicine and Associate Clinical Professor at the Medical University of South Carolina in Charleston, SC.
Richard K. Bogan
Dr. Bogan is the President of Bogan Sleep Consultants, LLC. He is also Associate Clinical Professor at the University of South Carolina School of Medicine and Associate Clinical Professor at the Medical University of South Carolina in Charleston, SC.
Dr. Bogan received his bachelor’s degree in chemistry from Wofford College and his MD degree from the Medical University of South Carolina in Charleston. He served his internship and residency, as well as Chief Medical Resident, at the University of Alabama Hospital and Clinics in Birmingham. Thereafter, he completed a fellowship and assistant professorship in the Pulmonary Division of the Department of Medicine at the University of Alabama School of Medicine. He has been certified by the American boards of Sleep Medicine, Internal Medicine, and Pulmonary Diseases.
Dr. Bogan has served as principal investigator on numerous clinical trials in the past and continues to do so now. He has a variety of publications and research interests that focus on topics such as narcolepsy, insomnia, sleep apnea, shift work sleep disorder, restless legs syndrome/periodic limb movement disorder, chronic fatigue/fibromyalgia, and circadian rhythm abnormality.
Dr. Jennifer Gordon was diagnosed with EGPA in 2014 and is the Vasculitis Patient Powered Research Network (VPPRN) Co-Principal Investigator and co-Lead Patient-Partner in the EGPA Registry. During this 30-minute CMEO Snack, Dr. Gordon will join Dr. Michael Wechsler, a national expert in EGPA. They will discuss how EGPA impacts patient quality of life and how clinicians can better detect and manage hidden symptoms of disease. Patient perspectives on delayed diagnosis, disease impact on their daily functioning, treatment options, and chronic steroid use will be included in the discussion.
0.5
12/29/2022
Michael E. Wechsler
Michael E. Wechsler is Professor of Medicine in the Division of Pulmonary, Critical Care and Sleep Medicine at National Jewish Health (NJH) in Denver, Director of the NJH/Cohen Family Asthma Institute, and Associate Vice President for Innovation and Industry Relations at NJH.
Michael E. Wechsler
Michael E. Wechsler is Professor of Medicine in the Division of Pulmonary, Critical Care and Sleep Medicine at National Jewish Health (NJH) in Denver, Director of the NJH/Cohen Family Asthma Institute, and Associate Vice President for Innovation and Industry Relations at NJH. In addition to clinical work in pulmonary and critical care medicine, Professor Wechsler’s research focuses on clinical and translational asthma with emphasis on clinical trials in asthma, novel asthma therapies, bronchial thermoplasty, asthma pharmacogenomics, and management of eosinophilic granulomatosis with polyangiitis (i.e. Churg-Strauss Syndrome). He has led studies focusing on novel biologic agents for asthma and related diseases, including benralizumab, dupilumab, mepolizumab, reslizumab, and tezepelumab. He has published more than 270 peer-reviewed manuscripts relating to asthma, EGPA, and eosinophilic lung diseases. He was a member of the Steering Committee and site Principal Investigator (PI) of the NIH-sponsored Asthma Clinical Research Network (ACRN, now called AsthmaNet), a multicenter asthma clinical trials consortium, and currently serves as the PI of the Denver site of the Precision Intervention in Severe/Exacerbating Asthma (PRECISE) network. A member of the American Society of Clinical Investigation and the Association of American Physicians, he has participated in many different task forces related to the study of eosinophilic lung diseases that were sponsored by the NIH, the FDA, the European Respiratory Society, and the International Eosinophil Society. He is currently Associate Editor of the journal Chest and has served as Associate Editor of the journal Allergy and on the editorial board of the European Journal of Clinical Investigation.
Dr. Wechsler received AB and MMSc degrees from Harvard University in Boston and an MD degree from McGill University in Montreal. He completed medical training at Beth Israel Hospital in Boston, and as part of the Harvard Combined Pulmonary and Critical Care Fellowship Training Program.</br.
Jennifer Gordon
Dr. Gordon was diagnosed with EGPA, a form of ANCA-associated vasculitis, in 2014. She holds a PhD in Pathology and spent nearly 30 years working as an NIH-funded biomedical researcher studying neurological disorders and infectious diseases.
Jennifer Gordon
Dr. Gordon was diagnosed with EGPA, a form of ANCA-associated vasculitis, in 2014. She holds a PhD in Pathology and spent nearly 30 years working as an NIH-funded biomedical researcher studying neurological disorders and infectious diseases, most recently as an Associate Professor in the Department of Neuroscience at Temple University School of Medicine in Philadelphia, Pennsylvania. She recently retired from academia and is now Head of Research & Development at Excision BioTherapeutics, a biotech start-up company developing CRISPR-based gene editing for the treatment of HIV and other viral diseases. Jenn is active in the vasculitis community. She is a patient partner in the Vasculitis Patient Powered Research Network (VPPRN) and a member of the VPPRN-VCRC EGPA Registry Joint Steering Committee. She currently hosts the EGPA Caf? Zoom Chat through the Vasculitis Foundation. You can find her blog online at www.vasculitides.com or follow her on Twitter at @vasculitides.
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