Alzheimer's Disease Education Hub

AD Diagnosis and Treatment Development

Alzheimer’s disease (AD), a heterogeneous, neurodegenerative condition with an insidious onset and slow progression, is the leading cause of disability and morbidity as well as the sixth-leading cause of death in the United States. Diagnoses is often challenging, and multimodal imaging strategies and other novel and emerging biomarkers can aid in differential diagnosis. Currently only symptomatic therapies are available, but recent clinical trials investigating disease-modifying therapies (DMTs) that could slow or reverse the progression of AD have shown great promise.

 

CME Outfitters is pleased to offer accredited CME/CE activities providing expert-led education on the pathogenesis of AD, current diagnostic criteria and guidelines for AD management, recent advances in the development of AD biomarkers, and the latest clinical evidence on emerging therapies.

Educational Activities

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Patient Education
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Deciphering Patient Selection Related to Current and Emerging Amyloid-Targeting Therapies (ATTs)

In this second installment of a two-part Journal Club series, An Expanded View of Alzheimer’s Disease Neuropathology: Translation to the Early Identification of Disease, expert faculty will evaluate the latest data from ATT clinical trials and discuss strategies for identifying appropriate patients based on both pathological and clinical characteristics to ensure timely and optimal management of patients with early symptomatic AD.

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Untangling the Data: pTau and Neurofibrillary Tangles as Part of Early Alzheimer’s Detection

In this first installment of a two-part Journal Club series, An Expanded View of Alzheimer’s Disease Neuropathology: Translation to the Early Identification of Disease, expert faculty will present the latest information on the neuropathological changes associated with AD, their relevance to the cognitive and functional decline of early AD, as well as the role of phosphorylated tau biomarkers as early indicators of both amyloid and tau accumulation.

 

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ARIA Alert: Timely Recognition in the Emergency Department

The first episode of this CMEO BriefCase series focuses on a patient case that requires differentiating ARIA from other conditions with a similar presentation in the emergency care setting, highlighting ARIA-related symptoms, listing other clinical manifestations of ARIA as described in clinical trials, and reviewing contraindicated medications for patients receiving an ATT.

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How to Treat ARIA in Emergency Settings: Timely Communication with Multi-Disciplinary Colleagues

The third and final episode of this CMEO BriefCase series focuses on a case involving a patient on an ATT presenting to the emergency department (ED), highlighting ED protocols to streamline care for patients with severe ARIA, recommendations for treatment and supportive care measures, global resources for guidance as the ATT landscape expands, management of ARIA according to best guidance, and communication with ATT-treating clinicians and radiologists.

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What to Do: My Patient in the ED May Have ARIA

The second episode of this CMEO BriefCase series focuses on a patient case that demonstrates real-world challenges such as obtainment of an accurate medical history, imaging needs and interpretations, and what to do if magnetic resonance imaging (MRI) is not accessible.

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Facilitating Definitive Diagnosis: Identification and Measurement of AD Pathophysiology

In this CME Outfitters Snack, expert faculty will discuss biomarker research findings presented at the Alzheimer’s Association International Conference (AAIC), review the identification and measurement of AD pathophysiology, examine a framework for evidencing biomarker profiles of AD, provide updates on prognostic performance and interpretation of biomarkers, and conduct a case-based discussion of clinical impacts and applications.

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Exploring New and Emerging ATTs to Inform Patient Selection and Increase Optimal Care in a Timely Manner

In this CME Outfitters Snack, expert faculty will review data presented at the Alzheimer’s Association International Conference (AAIC) and will focus on established, new, and emerging ATTs as well as a case-based discussion on clinical impacts and applications to provide point-of-care tactics that will have a positive impact on patient outcomes.

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Alzheimer’s Videos & Interactive 3D Models

In this video, Dr. Sharon Cohen discusses the formation of amyloid-ß aggregates and intracellular neurofibrillary tau tangles that are characteristic of Alzheimer’s Disease.

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Alzheimer’s Patient Education

Find useful learning aids to share with patients and their families.