Data from recent clinical trials for first-line combination options using immunotherapies for ovarian cancer (OC) can be challenging for clinicians with no experience selecting patients for combinatorial treatment approaches or using combination therapies for their patients. During this podcast, Drs. Richard Penson and Ramez Eskander will educate clinicians on the use of immune checkpoint inhibitors for the treatment of OC and the use of biomarker analyses to optimize patient selection.
Richard T. Penson, MD, MRCP, is a Medical Oncologist at Massachusetts General Hospital, and Associate Professor of Medicine at Harvard Medical School. A key opinion leader, Dr. Penson was a longstanding member of the Gynecologic Oncology Group Ovarian and Quality of Life Committees and now serves on the Foundation’s Investigator Council. He is the national Principal Investigator (PI) of the olaparib registration trial (SOLO-2) and the international PI of SOLO3, and the OVAL trial. He has taught on Harvard’s Practice of Medicine Course, the Bigelow General Medical Service at Massachusetts General Hospital, and is one of the Chairs of the Institutional Review Board of Dana-Farber Harvard Cancer Center.
Recent data has led to a debate of the most effective maintenance strategy for advanced OC. Emerging data utilizing novel approaches to maintenance both further complicates the debate and sheds new light on novel effective strategies for maintenance therapy for advanced OC, leaving clinicians struggling to adopt appropriate strategies. In order to ensure that clinical decisions align with the latest emerging data regarding maintenance therapy in OC, Drs. Richard Penson and Kathleen Moore will educate clinicians on the role of biomarkers in OC, incorporation of genetic testing, and interpretation of results as part of clinical practice.
Richard T. Penson, MD, MRCP, is a Medical Oncologist at Massachusetts General Hospital, and Associate Professor of Medicine at Harvard Medical School. A key opinion leader, Dr. Penson was a longstanding member of the Gynecologic Oncology Group Ovarian and Quality of Life Committees and now serves on the Foundation’s Investigator Council. He is the national Principal Investigator (PI) of the olaparib registration trial (SOLO-2) and the international PI of SOLO3, and the OVAL trial. He has taught on Harvard’s Practice of Medicine Course, the Bigelow General Medical Service at Massachusetts General Hospital, and is one of the Chairs of the Institutional Review Board of Dana-Farber Harvard Cancer Center.
During this podcast, sleep experts will be joined by a patient with narcolepsy who will share their experiences and insights. The candid discussion will include their diagnostic journey, experience with narcolepsy, and how their care team established treatment goals and measured treatment response over time. Additional patient case examples that require application of learned topics will also be discussed to better translate knowledge into practice.
Paul P. Doghramji, MD, FAAFP, is a Senior Family Physician with Collegeville Family Practice and Medical Director of Health Services for Ursinus College in Collegeville, Pennsylvania. Dr. Doghramji earned his medical degree from Jefferson Medical College in Philadelphia, Pennsylvania and completed residency in Family Practice at Chestnut Hill Hospital. He is a member of the American Academy of Family Physicians (AAFP) and was awarded the AAFP Fellowship Degree in 2005. He is a member of the Pennsylvania Academy of Family Physicians. Dr. Doghramji has been the recipient of the American Medical Association’s Physician Recognition Award in every qualifying year for 8 years. He has extensively published his research in peer-reviewed journals such as the American Journal of Medicine, Current Medical Research and Opinion, and Postgraduate Medicine. He has authored articles for numerous websites on topics such as sleep disorders, gout, rheumatoid arthritis (RA), biology of leg disorders, depression, chronic pain, health literacy, and diabetes. He is a co-author of the textbook Clinical Management of Insomnia, now in its second edition.
Dr. Anne Marie Morse is the Director of Child Neurology and Pediatric Sleep Medicine at Geisinger, Janet Weis Children’s Hospital. She has significant clinical and research experience and interest in children, adolescents, and adults with sleep wake disorders, particularly central disorders of hypersomnolence. In addition, her research interests extend more broadly to include investigating the relationship between sleep and neurologic and neurodevelopmental disorders. Dr Morse’s commitment to sleep health extends into the community. She has developed a school-based sleep education and surveillance program called Wake Up and Learn. This program was developed to provide education about sleep health and perform school-based sleep screening to improve recognition of pediatric sleep disorders in middle and high school students. It has now expanded to include learners in college, medical school, and medical residency programs with a clinical and health plan delivery, called Sleep to Be Well. Dr. Morse envisions a world where sleep can be acknowledged as the vital sign of health, wellness, and performance that it is designed to be.
During this podcast, sleep experts will discuss the differential diagnosis of narcolepsy, including underrecognized clinical presentations and diagnostic strategies for real-world use. The conversation will also include a breakdown of the classification of narcolepsy type 1 and type 2.
Lindsay McCullough is an Assistant Professor of Medicine and Sleep Medicine physician at Rush University Medical Center in Chicago, Illinois. Dr. McCullough joined RUSH in 2018 as a Sleep Medicine fellow. After completing her fellowship in 2019, she was recruited to join as faculty in the Division of General Internal Medicine and Section of Sleep Medicine. Before moving to Chicago, she earned her medical degree and completed her residency training at the University of Florida.
Dr. McCullough is the Associate Program Director for the Sleep Medicine Fellowship and a Fellow of the American College of Physicians. As a clinician educator and a person living with narcolepsy type 2, she is passionate about promoting healthy sleep and lifestyle habits to fellows, residents, and students, as well as other medical professionals, her patients, and to the general public. She also advocates for social support in addition to medical treatments for patients with sleep disorders. She works closely with the Rush Sleep Surgery team as a part of an innovative collaborative care model to improve the quality of care for patients with hypoglossal nerve stimulation therapy.
Dr. Anne Marie Morse is the Director of Child Neurology and Pediatric Sleep Medicine at Geisinger, Janet Weis Children’s Hospital. She has significant clinical and research experience and interest in children, adolescents, and adults with sleep wake disorders, particularly central disorders of hypersomnolence. In addition, her research interests extend more broadly to include investigating the relationship between sleep and neurologic and neurodevelopmental disorders. Dr Morse’s commitment to sleep health extends into the community. She has developed a school-based sleep education and surveillance program called Wake Up and Learn. This program was developed to provide education about sleep health and perform school-based sleep screening to improve recognition of pediatric sleep disorders in middle and high school students. It has now expanded to include learners in college, medical school, and medical residency programs with a clinical and health plan delivery, called Sleep to Be Well. Dr. Morse envisions a world where sleep can be acknowledged as the vital sign of health, wellness, and performance that it is designed to be.
Dr. Anne Marie Morse is the Director of Child Neurology and Pediatric Sleep Medicine at Geisinger, Janet Weis Children’s Hospital. She has significant clinical and research experience and interest in children, adolescents, and adults with sleep wake disorders, particularly central disorders of hypersomnolence. In addition, her research interests extend more broadly to include investigating the relationship between sleep and neurologic and neurodevelopmental disorders. Dr Morse’s commitment to sleep health extends into the community. She has developed a school-based sleep education and surveillance program called Wake Up and Learn. This program was developed to provide education about sleep health and perform school-based sleep screening to improve recognition of pediatric sleep disorders in middle and high school students. It has now expanded to include learners in college, medical school, and medical residency programs with a clinical and health plan delivery, called Sleep to Be Well. Dr. Morse envisions a world where sleep can be acknowledged as the vital sign of health, wellness, and performance that it is designed to be.
With the advent of ICI therapy and emerging ICI combination therapies, clinicians need to have knowledge of where and how maintenance therapy may play a role in improving PFS in EC. During this podcast, international gynecologic cancer experts Drs. Richard Penson and Nicoletta Colombo discuss the most recent data from these EC trials, focusing on how it has changed recommended practice patterns and how it should be incorporated into the care of patients with EC.
Richard T. Penson, MD, MRCP, is a Medical Oncologist at Massachusetts General Hospital, and Associate Professor of Medicine at Harvard Medical School. A key opinion leader, Dr. Penson was a longstanding member of the Gynecologic Oncology Group Ovarian and Quality of Life Committees and now serves on the Foundation’s Investigator Council. He is the national Principal Investigator (PI) of the olaparib registration trial (SOLO-2) and the international PI of SOLO3, and the OVAL trial. He has taught on Harvard’s Practice of Medicine Course, the Bigelow General Medical Service at Massachusetts General Hospital, and is one of the Chairs of the Institutional Review Board of Dana-Farber Harvard Cancer Center.