Negative symptoms

Sixth Annual Chair Summit Begins This Week

This week a Master Class for Neuroscience Development called the Chair Summit takes place in Tampa, FL (Sept 26-28, 2013). In the early days of medical training in Kos, students, trainees and medical colleagues would gather to discuss their cases and the latest science with Hippocrates.  This model of education was maintained throughout the centuries […]

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Beyond Dopamine: Glutamate as a Target in Schizophrenia

An interesting review in ISRN Pharmacology, a peer-reviewed, open access journal, describes that for the last 60 years, antipsychotic pharmacology targeting antagonism of dopamine (DA) D2 receptors have been the primary treatment choice for schizophrenia. The clinical improvement seen by both first and second generation antipsychotics has led to the dopamine hypothesis which theorizes that […]

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Negative symptoms and depression predict poorer psychological well-being in individuals with schizophrenia

A study published in Comprehensive Psychiatry evaluated the impact of negative symptoms and depression on psychological well-being in individuals with schizophrenia. A number of previous studies have demonstrated that negative symptoms are linked to lower rates of recovery in individuals with schizophrenia when defining recovery in terms of symptom remission, vocational outcome, and social functioning. […]

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Early Detection and Intervention in Psychosis Improves 10-Year Outcome

Early detection in first-episode psychosis confers advantages for negative, cognitive, and depressive symptoms after 1, 2, and 5 years, but longitudinal effects have been unknown. A new article  published in the American Journal of Psychiatry investigated the differences in symptoms and recovery after 10 years between regional health care sectors with and without a comprehensive […]

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Persistent negative symptoms in first-episode schizophrenia

A study published in Schizophrenia Research describes that negative symptoms, which are a core feature of schizophrenia, are generally understudied. Researchers evaluated the prevalence and stability of primary negative symptoms, and factors associated with persistent primary negative symptoms in a first-episode sample. Individuals (N=93) aged 18 to 55years presenting with first-episode schizophrenia-spectrum disorder were studied. […]

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