The emerging class of amyloid-targeting therapies (ATTs) are at the forefront of innovative approaches that promise to alter the course of Alzheimer’s disease (AD). However, the translation of these scientific advancements into clinical practice necessitates a well-informed clinical workforce adept …
Alzheimer’s disease (AD) presents a growing challenge in contemporary health care, with escalating prevalence and a significant burden imposed on patients, families, and health care systems globally. Early and accurate diagnosis of AD is essential for effective support and treatment. …
The inflammatory cytokine interleukin (IL)-23 has been implicated in the pathology of inflammatory bowel disease (IBD), a chronic inflammatory condition of the gastrointestinal tract. The stimulation of pathogenic Th-17 cell formation by IL-23 and the subsequent ongoing bowel inflammation via …
Patients with Crohn’s disease (CD) frequently experience bowel urgency, a symptom resulting in rushing to the bathroom and sometimes causing loss of bowel control. The symptom of bowel urgency dramatically impacts patient quality of life (QoL), and can lead to …
The Food and Drug Administration (FDA) recently approved immune checkpoint inhibitors (ICIs) for patients with advanced or recurrent endometrial cancer (EC) who did not respond to first-line treatment with chemotherapy. This led to several new trials of emerging therapies, including …
Studies demonstrate that approximately 65%-82% of patients with Crohn’s disease (CD) report at least some degree of bowel urgency, but this symptom is largely underrecognized by gastroenterologists and health care professionals (HCPs) caring for patients with inflammatory bowel disease (IBD). …
Chronic kidney disease (CKD) is a common comorbidity among patients with non-valvular atrial fibrillation (NVAF) and/or venous thromboembolism (VTE). Paradoxically, declining kidney function increases both thromboembolic and bleeding risks in patients with these conditions, requiring a fragile balance when implementing …
Anticoagulation for renally-impaired individuals with non-valvular atrial fibrillation (NVAF) or venous thromboembolism (VTE) often entails balancing the risk of vascular events (e.g., stroke, pulmonary embolism) with the dangers of excess bleeding. In this CME Outfitters BriefCase series, two expert clinicians …
Patients and health care professionals (HCPs) face additional challenges when the treatments prescribed for pain management (e.g., opioids) lead to substance use problems. HCPs must then re-evaluate treatment plans for acute, subacute, and chronic pain and encourage treatment for opioid …