Patients with narcolepsy experience excessive daytime sleepiness, cataplexy, disrupted night-time sleep, hypnagogic hallucinations, and sleep paralysis. Patients frequently cope with these symptoms for years, at great expense to their quality of life, and often have to see multiple specialists before …
Mycophenolate is the most common immunosuppressant used for preventing organ rejection in transplant recipients and is frequently employed in other disciplines, such as rheumatology. In response to the discovery of fetal teratogenicity associated with mycophenolate use during pregnancy, the FDA …
Narcolepsy is a chronic sleep disorder that affects approximately one in 2,000 individuals. The patient’s diagnostic journey is often long and complex, and narcolepsy frequently remains undiagnosed or is misdiagnosed as other conditions, including depression, schizophrenia, insomnia, or obstructive sleep …
The treatment landscape for hemophilia A and B is expanding with strategies and therapies to optimize efficacy, provide durable hemostasis restoration, and improve safety. These contemporary approaches to care have also led to new pathways and assays for clinical and …
The emerging class of amyloid-targeting therapies (ATTs) are at the forefront of innovative approaches that promise to alter the course of Alzheimer’s disease (AD). However, the translation of these scientific advancements into clinical practice necessitates a well-informed clinical workforce adept …
Alzheimer’s disease (AD) presents a growing challenge in contemporary health care, with escalating prevalence and a significant burden imposed on patients, families, and health care systems globally. Early and accurate diagnosis of AD is essential for effective support and treatment. …
The inflammatory cytokine interleukin (IL)-23 has been implicated in the pathology of inflammatory bowel disease (IBD), a chronic inflammatory condition of the gastrointestinal tract. The stimulation of pathogenic Th-17 cell formation by IL-23 and the subsequent ongoing bowel inflammation via …
Patients with Crohn’s disease (CD) frequently experience bowel urgency, a symptom resulting in rushing to the bathroom and sometimes causing loss of bowel control. The symptom of bowel urgency dramatically impacts patient quality of life (QoL), and can lead to …