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Equitable Prenatal Care: Preparing for Future Maternal RSV Vaccinations

Routine prenatal vaccine administration, such as that of influenza or tetanus, diphtheria, and acellular pertussis (Tdap), is a cornerstone of prenatal care and an important part of public health efforts to prevent disease. Respiratory syncytial virus (RSV) is a highly …

Racial/Ethnic Disparities in Cardiac Care: Real-World Strategies to Address Inequities in Treatment and Outcomes

Despite advances in the treatment and management of cardiovascular conditions such as hypertension and atrial fibrillation, significant disparities in both treatment and outcomes for patients from racial/ethnic underserved groups remain. In fact, race-based medicine, including prescribing specific treatments dependent on …

CMV Prophylaxis in Kidney Transplant: Examining New Solutions to an Old Problem

Post-transplant cytomegalovirus (CMV) infection afflicts as high as 80% of kidney organ transplant recipients, resulting in life-threatening direct complications, long-term negative outcomes, and significant morbidity and mortality. Current first-line antivirals administered to patients in post-treatment prophylaxis are associated with toxicity …

Population-Based Health in Practice: Addressing Health-Related Social Needs for Rural-Residing Patients

Rural-residing patients encounter roadblocks when they need health care. These patients likely live a considerable geographic distance from providers and facilities, the facilities themselves are far from one another, and there is a shortage of clinicians. Providers who serve in …

Clean-Up on IL-23: Integrating the Science of Inflammatory Targets into Treatment Decision-making in IBD

Recently, interleukin (IL)-23 and the inflammatory IL-23/T-helper (Th)-17 axis have been identified as central drivers of inflammation related to inflammatory bowel disease (IBD). Science in the field of cytokine-targeting therapies, specifically in the field of IL-23 P19 targeting agents, is …

Employing Multi-Modal Pain Management in a Low-Resource Setting

The management of pain is challenging for providers, added to that the challenges of communicating with patients affected by pain in compassionate, non-stigmatizing ways that facilitate shared decision-making and individualized care. Multimodal approaches that minimize risks and maximize benefits are …

Actionable Opportunities for Molecularly Classified Endometrial Cancers

Multiple clinical practice guidelines for the treatment of endometrial cancer (EC) recommend consideration of molecular testing, particularly for high-grade tumors. Yet despite its prognostic value, molecular classification is not always a part of standard risk assessment in EC. Clinical uptake …

Overcoming Obstacles: Expert Perspectives on the Diagnosis and Management of Familial Chylomicronemia Syndrome

Familial chylomicronemia syndrome (FCS) is an autosomal recessive disorder that affects approximately 3,000 – 5,000 individuals worldwide. Though quite rare, this disorder, characterized by elevated chylomicron levels and severe hypertriglyceridemia, presents a significant challenge both for the affected patients, as …