The Myth of Schizophrenia as a Progressive Brain Disease
Schizophrenia has historically been considered to be a deteriorating disease, a view reinforced by recent MRI findings of progressive brain tissue loss over the early years of illness. Zipursky and colleagues challenge this concept. Schizophrenia Bulletin [More…]
Read MoreThe Nature of Relapse in Schizophrenia
Discontinuation of treatment in schizophrenia results in very high relapse rates, even after a single psychotic episode. A new review in BMC Psychiatry asserts that multiple relapses characterze the course of illness in most patients with schizophrenia, yet the nature of these episodes has not been extensively researched and clinicians may not always be aware […]
Read MoreEarly Detection and Intervention in Psychosis Improves 10-Year Outcome
Early detection in first-episode psychosis confers advantages for negative, cognitive, and depressive symptoms after 1, 2, and 5 years, but longitudinal effects have been unknown. A new article published in the American Journal of Psychiatry investigated the differences in symptoms and recovery after 10 years between regional health care sectors with and without a comprehensive […]
Read MoreChair Summit Meeting Highlights – available now in HORM
Article series from the 3rd Annual Chair Summit, The Master Class for Neuroscience Professional Development (Chair Summit) available now in Health Outcomes Research in Medicine journal (HORM) The continuing professional development of clinicians protects one of our nation’s most precious human resources—a well-trained force of health care workers. Making decisions to manage illness and handle […]
Read MorePersistent negative symptoms in first-episode schizophrenia
A study published in Schizophrenia Research describes that negative symptoms, which are a core feature of schizophrenia, are generally understudied. Researchers evaluated the prevalence and stability of primary negative symptoms, and factors associated with persistent primary negative symptoms in a first-episode sample. Individuals (N=93) aged 18 to 55years presenting with first-episode schizophrenia-spectrum disorder were studied. […]
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