IrAEs in Emergency Medicine: Have You Missed It?

This activity is part of a series


Jimmy L. Pruitt III, PharmD, BCPS, BCCCP, BCEMP
Emergency Medicine Clinical Pharmacy Specialist
Atrium Health Carolinas Medical Center
Jimmy L. Pruitt III, PharmD, BCPS, BCCCP, BCEMP

Jimmy L. Pruitt III, PharmD, BCPS, BCCCP, BCEMP, is originally from Orlando, Florida, and received his Doctor of Pharmacy from Presbyterian College School of Pharmacy in 2017. He completed a PGY-1 pharmacy residency at Florida Hospital Orlando and then went on to Grady Health System in Atlanta, Georgia, for his PGY2 emergency medicine residency. Dr. Pruitt is currently an emergency medicine clinical pharmacy specialist at the Medical University of South Carolina (MUSC) in Charleston, South Carolina. He was awarded Grady Pharmacist of the Year in 2019 as a PGY2 emergency medicine resident, which was a first in the program’s 30+ year history. In 2020, he obtained Board-Certified Pharmacotherapy Specialist (BCPS) and Board-Certified Critical Care Pharmacist (BCCCP) recognition. Also, in 2020, he won the Society of Academic Emergency Medicine (SAEM) Got Talent competition for his educational series “Pharmacy Friday Pearls,” which was the first time a pharmacist won the event. In 2021, Dr. Pruitt was honored with the Excellence in Diversity award from MUSC College of Pharmacy, was Presbyterian College School of Pharmacy (PCSP) Alumni of the Year, and was keynote speaker for the 2021 PCPS graduation. His professional interests include cardiac arrest, shock syndromes, trauma, and hosting his podcast Pharm So Hard. Dr. Pruitt obtained board certification in emergency medicine in May 2023.

Monica Wattana, MD, FAAEM
Associate Professor of Emergency Medicine
Director of Education
University of Texas MD Anderson Cancer Center, Houston, TX
Monica Wattana, MD, FAAEM

Monica Kathleen Wattana completed residency training in Emergency Medicine at UCLA/Olive View and was first to complete a fellowship in Oncologic Emergency Medicine at UT MD Anderson Cancer Center. Upon fellowship completion, she stayed on as faculty and currently is an Associate Professor within the Department of Emergency Medicine. Dr. Wattana serves as the Director of Education for the department and is in charge of all educational initiatives including trainee clinical rotations and the Oncologic Emergency Medicine Fellowship. She also co-chairs the annual MD Anderson Oncologic Emergency Medicine Conference. She is a content expert in the area of oncologic emergency medicine education and clinical practice and has been invited as a speaker for multiple international and national medical conferences.

Statement of Need

Immuno-oncology agents, such as immune checkpoint inhibitors (ICIs), are being increasingly used for the treatment of cancer.  Treatment with ICIs can result in immune-related adverse events (irAEs) which require prompt recognition and treatment. However, emergency department (ED) management of irAEs is suboptimal due to lack of clinician familiarity with irAE presentation and onset and the overlap of irAE presentation with other common medical complaints. ED pharmacists play an important role in the management of drug-related adverse events, however, education is needed to improve pharmacist ability to identify patients with a history of ICI treatment, and to recognize and manage irAEs.

In this CMEO BriefCase, Drs. Pruitt and Wattana will guide learners through a patient case scenario reviewing the recognition of ICI exposure through focused medication history, signs and symptoms of irAEs, and principles of early, appropriate management and the importance of consultation with an oncology care team. This program will focus on the role of the ED pharmacist in making timely interventions for patients with irAEs seen in the emergency department including strategies for engaging with ED team members and for setting the patient up for a successful transition in care.

Learning Objectives

Recommend escalating treatment interventions and consultation to appropriate specialists for complex irAE scenarios.

Financial Support

Supported by an educational grant from Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.

Target Audience

Pharmacists in outpatient, ambulatory, or community care settings.

Credit Information

Jointly Accredited Provider

In support of improving patient care, CME Outfitters, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Pharmacists (ACPE) 0.5

This application-based activity is approved for 0.5 contact hours (0.05 CEUs) of continuing pharmacy credit.
Activity UAN: JA0007185-0000-23-013-H01-P

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process.

Dr. Pruitt reports no financial relationships to disclose.

Dr. Wattana reports no financial relationships to disclose.

Disclosures were obtained from the CME Outfitters, LLC staff: No disclosures to report:

  • Joshua Caballero PharmD, BCPP, FCCP (peer reviewer)
  • Thomas Mitchell (planning committee)
  • Julie Strickland, PharmD (planning committee)
  • Susan H. Yarbrough, CHCP (planning committee)
  • Sandra Caballero, PharmD (planning committee)
  • Sharon Tordoff (planning committee)

Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

Obtaining Credit

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Questions about this activity?

Call us at 877.CME.PROS (877.263.7767).


IrAEs in Emergency Medicine: Have You Missed It?
Event Date: 03/31/2023 at 5:00 am EST