CME Snack

Accounting for the Impact of EGPA on Patient Quality of Life

Launch Date
12/29/2022
Credit Amount
1.00 Hours
Credit Expires
12/29/2023
This activity is part of a series

Faculty

Michael E. Wechsler, MD, MMSc
Professor of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine
Director, The Cohen Family Asthma Institute, National Jewish Health, Denver, CO
Michael E. Wechsler, MD, MMSc

Michael E. Wechsler is Professor of Medicine in the Division of Pulmonary, Critical Care and Sleep Medicine at National Jewish Health (NJH) in Denver, Director of the NJH/Cohen Family Asthma Institute, and Associate Vice President for Innovation and Industry Relations at NJH. In addition to clinical work in pulmonary and critical care medicine, Professor Wechsler’s research focuses on clinical and translational asthma with emphasis on clinical trials in asthma, novel asthma therapies, bronchial thermoplasty, asthma pharmacogenomics, and management of eosinophilic granulomatosis with polyangiitis (i.e. Churg-Strauss Syndrome). He has led studies focusing on novel biologic agents for asthma and related diseases, including benralizumab, dupilumab, mepolizumab, reslizumab, and tezepelumab. He has published more than 270 peer-reviewed manuscripts relating to asthma, EGPA, and eosinophilic lung diseases. He was a member of the Steering Committee and site Principal Investigator (PI) of the NIH-sponsored Asthma Clinical Research Network (ACRN, now called AsthmaNet), a multicenter asthma clinical trials consortium, and currently serves as the PI of the Denver site of the Precision Intervention in Severe/Exacerbating Asthma (PRECISE) network. A member of the American Society of Clinical Investigation and the Association of American Physicians, he has participated in many different task forces related to the study of eosinophilic lung diseases that were sponsored by the NIH, the FDA, the European Respiratory Society, and the International Eosinophil Society. He is currently Associate Editor of the journal Chest and has served as Associate Editor of the journal Allergy and on the editorial board of the European Journal of Clinical Investigation.<br.
Dr. Wechsler received AB and MMSc degrees from Harvard University in Boston and an MD degree from McGill University in Montreal. He completed medical training at Beth Israel Hospital in Boston, and as part of the Harvard Combined Pulmonary and Critical Care Fellowship Training Program.</br.

Jennifer Gordon, PhD
Patient Partner, Vasculitis Foundation
Co-Principal Investigator, Vasculitis Patient Powered Research Network, Kansas City, MO
Jennifer Gordon, PhD

Dr. Gordon was diagnosed with EGPA, a form of ANCA-associated vasculitis, in 2014. She holds a PhD in Pathology and spent nearly 30 years working as an NIH-funded biomedical researcher studying neurological disorders and infectious diseases, most recently as an Associate Professor in the Department of Neuroscience at Temple University School of Medicine in Philadelphia, Pennsylvania. She recently retired from academia and is now Head of Research & Development at Excision BioTherapeutics, a biotech start-up company developing CRISPR-based gene editing for the treatment of HIV and other viral diseases. Jenn is active in the vasculitis community. She is a patient partner in the Vasculitis Patient Powered Research Network (VPPRN) and a member of the VPPRN-VCRC EGPA Registry Joint Steering Committee. She currently hosts the EGPA Caf? Zoom Chat through the Vasculitis Foundation. You can find her blog online at www.vasculitides.com or follow her on Twitter at @vasculitides.

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Statement of Need Learning Objectives Financial Support Target Audience Credit Information Disclosure Declaration Obtaining Credits

Statement of Need

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of vasculitis that often goes unrecognized or misdiagnosed. Patients with EGPA go an average of 4 years between initial symptom onset and diagnosis. Clinicians fail to recognize early, non-specific symptoms of EGPA, delaying treatment that could prevent eosinophil-mediated organ damage. Patients with EGPA are frequently treated with corticosteroids which can result in adverse events that compound the impact of the disease. Newer treatments targeting IL-5 and eosinophil activity may allow for corticosteroid tapering or discontinuation and improvement in patient quality of life. Clinicians should utilize shared decision making to develop treatment plans that prioritize patient-centered goals for managing disease symptoms and minimizing medication toxicity.

Dr. Jennifer Gordon was diagnosed with EGPA in 2014 and is the Vasculitis Patient Powered Research Network (VPPRN) Co-Principal Investigator and co-Lead Patient-Partner in the EGPA Registry. During this 30-minute CMEO Snack, Dr. Gordon will join Dr. Michael Wechsler, a national expert in EGPA. They will discuss how EGPA impacts patient quality of life and how clinicians can better detect and manage hidden symptoms of disease. Patient perspectives on delayed diagnosis, disease impact on their daily functioning, treatment options, and chronic steroid use will be included in the discussion.

Learning Objectives

At the end of this CME/CE activity, participants should be able to assess how EGPA and associated conditions impact patient QoL.

Financial Support

This educational activity is supported by an educational grant from GSK.

Target Audience

Physicians, PAs, nurse practitioners, nurses, and pharmacists specializing in rheumatology, allergy/immunology, pulmonology, nephrologist, internal medicine, and primary care medicine.

Credit Information

Jointly Accredited Provider

In support of improving patient care, CME Outfitters, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physicians (ACCME)

CME Outfitters, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. CME Outfitters, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

MIPS Improvement Activity

This activity counts towards MIPS Improvement Activity requirements under the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

Royal College MOC

Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

ABIM MOC

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC point in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Pharmacists/Pharmacy Tech (ACPE)

This application-based activity is approved for 1.0 contact hour (0.10 CEUs) of continuing pharmacy credit.
Activity UAN: JA0007185-0000-22-166-H01-P

Nurses (ANCC)

This activity is designated for 1.0 contact hour.

Note to Nurse Practitioners

Nurse Practitioners can apply for AMA PRA Category 1 Credit ™ through the American Academy of Nurse Practitioners (AANP). AANP will accept AMA PRA Category 1 Credit ™ from organizations accredited by the Accreditation Council for Continuing Medical Education. Nurse practitioners can also apply for credit through their state boards.

PAs (AAPA)

CME Outfitters, LLC, has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits. Approval is valid until the expiration date listed above. PAs should only claim credit commensurate with the extent of their participation.

Note for California Nurses

This continuing nursing education activity was approved by the California Board of Registered Nursing. CME Outfitters LLC’s provider number is CEP15510.

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process.

Dr. Wechsler reports the following financial relationships: Advisory Board/Consultant: Amgen Inc.; AstraZeneca; Avalo Therapeutics, Inc.; Boehringer Ingelheim; Cerecor Inc.; Cohero Health, Inc.; CytoReason LTD; Eli Lilly and Company; Equillium Bio; GSK; Incyte; Kinaset Therapeutics; Novartis Pharmaceuticals Corporation; Om Pharma; Phylaxis Bioscience, LLC; PULMATRiX, Inc.; RAPT Therapeutics; Regeneron Pharmaceuticals Inc.; Restorbio; Roche/Genentech, Inc.; Sanofi/Genzyme.; Sentien Biotechnologies, Inc.; Sound Biologics; Tetherex Pharmaceuticals; Teva Pharmaceuticals USA, Inc.; and Upstream Bio. Research Support: Amgen Inc.; AstraZeneca; Avalo Therapeutics, Inc.; GSK; Regeneron Pharmaceuticals Inc.; and Sanofi/Genzyme. Speakers Bureau: AstraZeneca; GSK; Regeneron Pharmaceuticals Inc.; and Sanofi.

Dr. Gordon reports the following financial relationships: Consultant/Employee/Stock Options: Excision BioTherapeutics, a biotech start-up company developing gene editing technology for the treatment of infectious disease. This relationship is unrelated to this CE activity.

The following peer reviewer and CME Outfitters staff have no financial relationships:

  • Michael Franks, APRN, AGACNP-BC, FNP-BC (peer reviewer)
  • Thomas Mitchell (planning committee)
  • Kasey Brandt, PharmD (planning committee)
  • Susan H. Yarbrough, CHCP (planning committee)
  • Sandra Caballero, PharmD (planning committee)
  • Sharon Tordoff (planning committee)

Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

Obtaining Credits

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Questions about this activity?

Call us at (877) CME-PROS or (877) 263-7767.

SN-180-122922-06

 

Activities in the Series

For Clinicians
03/27/2023

Diagnosing EGPA: Recognizing Signs and Symptoms of the Disease

0.5
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Accounting for the Impact of EGPA on Patient Quality of Life
Event Date: 12/29/2022
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