A New Dawn in the Management of Idiopathic Hypersomnia: An Adaptive Learning Approach to Diagnosis and Implementing Clinical Trial Updates


Nancy R. Foldvary-Schaefer, DO, MS, FAASM, FAAN, FAES, FACNS
Professor of Neurology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Director, Cleveland Clinic Sleep Disorders Center, Cleveland, OH
Nancy R. Foldvary-Schaefer, DO, MS, FAASM, FAAN, FAES, FACNS

Dr. Nancy Foldvary-Schafer currently serves as Director of the Sleep Disorders Center and staff in the Adult Epilepsy Center at the Cleveland Clinic in Cleveland, Ohio. She is Professor of Medicine at the Cleveland Clinic Lerner College of Medicine. Certified by the American Board of Neurology and Psychiatry in Neurology, Clinical Neurophysiology, Sleep Medicine and Epilepsy Medicine, she has treated patients with sleep disorders and epilepsy at the Cleveland Clinic since 1995. Under her leadership, the Cleveland Clinic Sleep Medicine program has undergone substantial growth including the establishment of 10 sleep laboratories and a multidisciplinary physician team spanning across neurology, psychiatry, psychology, pulmonary medicine, family and internal medicine, and pediatric specialties. She has served as a lead investigator on epilepsy, sleep apnea and narcolepsy clinical trials and has written extensively on sleep and epilepsy and women’s health and epilepsy. In 2016, Dr. Foldvary-Schaefer was appointed to the Cleveland Clinic Board of Governors. She serves on numerous national, regional, and local committees and is the author of two books and the lead editor of two books including Sleep Disorders: A Case a Week from the Cleveland Clinic, 2nd Edition, published in 2019. Also, in 2019, she received the Women’s Professional Staff Association Champion Award. She is the recipient of a $2.1 million philanthropic gift to advance education and awareness of sleep disorders.

Statement of Need

Idiopathic hypersomnia (IH) is a chronic, debilitating sleep disorder mainly characterized by excessive daytime sleepiness (EDS) as well as prolonged nocturnal sleep and/or daytime naps, unrefreshing sleep, sleep inertia, and autonomic dysfunction. These symptoms, in turn, often result in diminished psychosocial functioning, cognitive dysfunction, school/work performance, and quality of life (QoL), subsequently impacting family, friends, and work colleagues, as well as public health and safety. Contributing to the debilitation caused by IH is the failure of health care practitioners (HCPs) to accurately diagnose IH in a timely manner. In fact, an accurate diagnosis can often take years, leaving patients with IH struggling with personal, work, and psychosocial dysfunction in the interim.

While advances in sleep medicine have resulted in the first and only FDA-approved therapy for IH, incorporating this therapy into practice and monitoring treatment efficacy requires best practices. Please join Dr. Foldvary-Schaefer in this adaptive learning activity for a personalized journey through the latest clinical evidence for IH, strategies to transition patients to new therapies, and evidence-based tools to assess symptom severity and treatment effectiveness.

Learning Objectives

At the end of this CME/CE activity, participants should be able to:

  • Recognize the burden of IH.
  • Utilize validated tools to measure the impact of IH on function and QoL.
  • Assess the efficacy and safety data for novel agents to manage IH.

Financial Support

Supported by an educational grant from Jazz Pharmaceuticals, Inc.

Target Audience

Sleep specialists, pulmonologists, psychiatrists, neurologists, primary care providers, physician associates (PAs), nurse practitioners (NPs), nurses, and pharmacists

Credit Information

Jointly Accredited Provider

In support of improving patient care, CME Outfitters, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Interprofessional (IPCE) 1.0

This activity was planned by and for the healthcare team, and learners will receive 1.0 Interprofessional Continuing Education (IPCE) Credit for learning and change.

Physicians (ACCME) 1.0

CME Outfitters, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses (ANCC) 1.0

This activity is designated for 1.0 contact hour.

Note for California Nurses

This continuing nursing education activity was approved by the California Board of Registered Nursing. CME Outfitters, LLC’s provider number is CEP15510.

Pharmacists (ACPE) 1.0

This application-based activity is approved for 1.0 contact hour (0.10 CEUs) of continuing pharmacy credit.
Activity UAN: JA0007185-0000-23-016-H01-P

PAs (AAPA) 1.0

CME Outfitters, LLC, has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits. Approval is valid until the expiration date listed above. PAs should only claim credit commensurate with the extent of their participation.


Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 medical knowledge MOC point in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

MIPS Improvement Activity

Completion of this accredited CME activity meets the expectations of an Accredited Safety or Quality Improvement Program (IA_PSPA_28) for the Merit-based Incentive Payment Program (MIPS). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

Royal College MOC

Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Foldvary-Schaefer reports the following financial relationships: Advisory Board: Jazz Pharmaceuticals, Inc. (Publication Committee). Research Support: Jazz Pharmaceuticals, Inc.; Suven Pharmaceuticals Limited; Takeda Pharmaceuticals U.S.A., Inc.; and Vanda Pharmaceuticals

The following Peer Reviewer and CME Outfitters staff reports no financial relationships:

  • Michael Franks, APRN, AGACNP-BC, FNP-BC (peer reviewer)
  • Kashemi D. Rorie, PhD (planning committee)
  • Evan Luberger (planning committee)
  • Susan H. Yarbrough, CHCP (planning committee)
  • Sandra Caballero, PharmD (planning committee)
  • Sharon Tordoff (planning committee)

Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

Obtaining Credits

Post-tests, credit request forms, and activity evaluations must be completed online (requires free account activation), and participants can print their certificate or statement of credit immediately (75% pass rate required). This website supports all browsers except Internet Explorer for Mac. For complete technical requirements and privacy policy, visit our Privacy & Confidentiality page.

Questions about this activity?

Call us at (877) CME-PROS or (877) 263-7767.


A New Dawn in the Management of Idiopathic Hypersomnia: An Adaptive Learning Approach to Diagnosis and Implementing Clinical Trial Updates
Event Date: 01/18/2023