Chronic lymphocytic leukemia (CLL) has undergone a remarkable therapeutic transformation with the availability of highly effective targeted therapies. However, molecular testing and the integration of prognostic and predictive biomarkers into treatment decisions remain inconsistent, particularly outside tertiary care centers. Because …
Idiopathic hypersomnia (IH) is a life-disrupting condition characterized by excessive daytime sleepiness (EDS) that makes waking up a daily struggle, limits productivity, and erodes overall quality of life. For many patients with IH, the journey to diagnosis is long and …
For people living with ulcerative colitis (UC), cycles of remission and relapse can disrupt daily life and complicate long-term management. Sphingosine-1-phosphate receptor modulators (S1Prms) are a new class of targeted oral therapies with the potential to reduce colonic inflammation and …
Complicated urinary tract infections (cUTIs) represent one of the most challenging and rapidly evolving areas of infectious disease management. Often more severe and harder to treat than standard UTIs, cUTIs are associated with underlying structural or functional abnormalities of the …
Fibrosis remains one of the greatest unmet needs in inflammatory bowel disease (IBD), contributing to irreversible structural bowel damage, complications, and long-term morbidity despite advances in anti-inflammatory therapies. Many gastroenterologists and multidisciplinary gastrointestinal (GI) care teams lack confidence in recognizing …
Despite the availability of a safe and effective recombinant zoster vaccine (RZV) for herpes zoster (HZ), vaccination uptake and series completion remain insufficient, leaving many at-risk individuals—particularly older adults, immunocompromised patients, and underserved populations—vulnerable to preventable disease and its impact …
Lupus nephritis (LN) is one of the most consequential organ manifestations of systemic lupus erythematosus (SLE), occurring in approximately 40% to 60% of patients, most often within the first 5 years of diagnosis, and progressing to end-stage kidney disease in …
Although treatment advances in inflammatory bowel disease (IBD) have improved symptom control, many patients continue to experience progressive structural bowel damage and systemic complications that are not adequately addressed in routine care. Gastroenterologists and multidisciplinary gastrointestinal (GI) care teams often …
Systemic health inequities disproportionately impact underserved racial and ethnic populations, leading to higher morbidity, mortality, and reduced quality of life. Socioeconomic disadvantages, racial bias, and barriers to care contribute to these disparities, yet they often go unnoticed by health care …