Generalized myasthenia gravis (gMG) is a chronic neuromuscular disorder that results from destruction of the neuromuscular junction by pathogenic autoantibodies, partially through the actions of the neonatal Fc receptor (FcRn). Traditional therapies only partially alleviate the heavy disease burden and …
Acromegaly presents a diagnostic and management challenge due to its gradual onset, diverse symptoms, and complex treatment landscape. Delays in diagnosis and suboptimal care lead to prolonged morbidity and increased mortality. However, emerging therapies, including novel oral options, offer new …
Acromegaly presents a diagnostic and management challenge due to its gradual onset, diverse symptoms, and complex treatment landscape. Delays in diagnosis and suboptimal care lead to prolonged morbidity and increased mortality. However, emerging therapies, including novel oral options, offer new …
Lennox-Gastaut syndrome (LGS) is a severe epileptic encephalopathy with early childhood manifestations that results in developmental delays, behavioral issues, and cognitive dysfunction. Alongside treatment-resistant seizures, patients with LGS experience a wide range of non-seizure symptoms that severely impact quality of …
Early detection and treatment of human immunodeficiency virus (HIV) and hepatitis B and C (HBV, HCV) are paramount to mitigating the damage associated with these diseases, thus allowing patients to live longer, healthier lives; but many patients do not receive …
More than 32 million adults in the United States currently have diabetes, 90% of whom have type 2 diabetes (T2D) which can lead to both microvascular and macrovascular complications, and greatly compromise health-related quality of life (HRQoL) and confer significant …
Early detection and treatment of human immunodeficiency virus (HIV) and hepatitis B and C (HBV, HCV) are paramount to mitigating the damage associated with these diseases, thus allowing patients to live longer, healthier lives; but many patients do not receive …
Treatment for primary biliary cholangitis (PBC), a “common rare” chronic autoimmune disease of the intrahepatic bile ducts, is frequently hampered by missed or delayed diagnosis, as symptoms of PBC are often attributed to other conditions. This suboptimal recognition enables unchecked …
Treatment for primary biliary cholangitis (PBC), a “common rare” chronic autoimmune disease of the intrahepatic bile ducts, is frequently hampered by missed or delayed diagnosis, as symptoms of PBC are often attributed to other conditions. This suboptimal recognition enables unchecked …