Familial chylomicronemia syndrome (FCS) is an autosomal recessive disorder that affects approximately 3,000 – 5,000 individuals worldwide. Though quite rare, this disorder, characterized by elevated chylomicron levels and severe hypertriglyceridemia, presents a significant challenge both for the affected patients as well as the clinicians who are tasked with managing it. FCS is associated with debilitating, and sometimes even fatal, symptoms and associated conditions, including recurrent abdominal pain and acute pancreatitis, as well as a psychological burden related to stringent dietary restrictions. Thus, it is imperative that clinicians have the knowledge required to correctly identify this condition early and implement a guideline-directed management plan in order to improve the patient’s quality of life and clinical outcomes.
In this enduring CME Outfitters Webcast, expert faculty will guide learners through the diagnostic process for FCS, discuss approaches to adhering to stringent dietary guidance, and introduce strategies to effectively implement multidisciplinary management for this condition. They will also detail new and emerging treatment options to help keep all members of the health care team up to date with the latest scientific advances in this field.
This activity is supported by an educational grant from Ionis Pharmaceuticals, Inc.
Physicians (specializing in endocrinology, lipidology, gastroenterology, cardiology, and primary care, including internal medicine, family medicine, and pediatrics), physician associates (PAs), nurse practitioners (NPs), nurses, pharmacists, and dietitians
In support of improving patient care, CME Outfitters, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
This activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education Credit for learning and change.
CME Outfitters, LLC, designates this Enduring Material for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
This activity is designated for 1.00 contact hours.
This application-based activity is approved for 1.00 contact hours ( 0.1 CEUs) of continuing pharmacy credit ( JA0007185-0000-23-124-H01-P ).
CME Outfitters, LLC, has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credits. Approval is valid until 11/15/2024. PAs should only claim credit commensurate with the extent of their participation.
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 medical knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Completion of this accredited CME activity meets the expectations of an Accredited Safety or Quality Improvement Program (IA_PSPA_28) for the Merit-based Incentive Payment Program (MIPS). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.
Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.
It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process.
Dr. Hegele reports the following financial relationships:
Advisory Board: Amgen Inc.; Arrowhead Pharmaceuticals, Inc.; HLS Therapeutics Inc.; Ionis Pharmaceuticals; and Novartis AG
Consultant: Amgen Inc.; Arrowhead Pharmaceuticals, Inc.; Boston Heart Diagnostics Corporation; HLS Therapeutics Inc.; Ionis Pharmaceuticals; Medison Pharma; Medpace; Novartis AG; Pfizer Inc.; and Regeneron Pharmaceuticals. Inc.
Dr. Chait reports the following financial relationships:
Advisory Board: LIB Therapeutics (Data Safety Management Board)
Consultant: Partnership For Health Analysis Research
Mr. Wertalik reports no financial relationships to disclose.
Dr. Witztum reports the following financial relationships:
Consultant: Ionis Pharmaceuticals
Stock Shareholder: Ionis Pharmaceuticals
Other financial or material support:
Patents on oxidation specific antibodies held by UCSD; cofounder of Oxitope and Kleanthi (no monetary value)
Disclosures were obtained from the following peer reviewer and CME Outfitters, LLC, staff, with no disclosures to report:
Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.
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