Global Guidelines and Strategies for HIV Screening and Diagnosis

Despite major advances in human immunodeficiency virus (HIV) management—including effective antiretroviral therapy (ART) and long-acting injectables—gaps in screening, testing, and diagnosis continue to limit patient outcomes and prevention efforts. Many clinicians, particularly in primary care and community settings, face challenges integrating evolving global testing guidelines into practice, leading to inconsistent screening, delayed diagnosis, and missed opportunities for rapid linkage to care. These issues are further compounded by stigma, bias, resource limitations, and regional disparities in access to care. To address these barriers, clinicians need practical, regionally relevant education that strengthens their ability to implement evidence-based HIV testing strategies, adopt routine screening, and integrate rapid-start/same-day ART workflows. Equipping clinicians with effective communication techniques and culturally responsive approaches is essential to improving patient engagement, increasing HIV testing uptake, and ultimately reducing HIV transmission and disease burden.

In this CMEO Snack, expert faculty will discuss the role of HIV testing in connecting individuals to the care continuum, with a focus on global testing guidelines. Faculty will also explore strategies for increasing HIV testing uptake across the socioeconomic spectrum by reviewing effective communication approaches to address stigma, bias, and access/resource barriers; comparing testing practices and guideline recommendations by region; and outlining rapid-start and same-day ART initiation workflows following diagnosis.

At the conclusion of this activity, learners will be able to better:

•  Integrate guideline recommendations for HIV testing into routine practice

This activity has been supported by an independent educational grant from Gilead Sciences, Inc.

HIV/infectious disease (ID) specialists, primary care practitioners (PCPs), general practitioners (GPs), physician associates (PAs), nurse practitioners (NPs), nurses, and pharmacists in key regions globally: United States, Europe, Africa, and Asia

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Faculty

Dr. Blackstock reports the following financial relationships:

Advisory Board: Health Equity Advisory Board – ViiV Healthcare

Speakers Bureau: Gilead Sciences, Inc. and ViiV Healthcare

Prof. Orkin reports the following financial relationships:

Advisory Board: Gilead Sciences, Inc.; GSK; MSD (Merck Sharp & Dohme); and ViiV Healthcare

Grants: Gilead Sciences, Inc.; GSK; MSD (Merck Sharp & Dohme); and ViiV Healthcare

Speakers Bureau: Bavarian Nordic; Gilead Sciences, Inc.; GSK; MSD (Merck Sharp & Dohme); and ViiV Healthcare

Dr. Solomon reports the following financial relationships:

Advisory Board: Merck & Co., Inc.

Grants: Abbott Laboratories

Research Support: Abbott Laboratories

Other financial or material support: Honorarium from Gilead Sciences, Inc. to serve on a review committee

Dr. Titanji reports no financial relationships to disclose.

Patient Planners

Mr. Raif Derrazi reports the following financial relationships:

Advisory Board: ViiV Healthcare

Other financial or material support: Occasional Partnerships: ViiV Healthcare

Ms. Angelina Namiba reports no financial relationships to disclose.

Mr. Prasanth Veerapandiyan reports no financial relationships to disclose.

The following individuals have no financial relationships to disclose:

Rebecca Vargas-Jackson, MD (Peer Reviewer)
Albert Eubanks, Jr., RN (Peer Reviewer)
Susan Perry (Planning Committee)
Estelle Perera (Planning Committee)
Andrea Perseghin, EdD (Planning Committee)
Sandra Caballero, PharmD (Planning Committee)
Sharon Tordoff (Planning Committee)

*All identified conflicts of interest have been mitigated.

Unlabeled Use Disclosure
Faculty of this CME/CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices. CME Outfitters, LLC, the faculty, planners, and reviewers do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.

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