Educational Animations Hub

View this animation for an overview of the impact and pervasive nature of shingles.

Pathophysiology of Alzheimer’s Disease

In this video, Dr. Sharon Cohen discusses the formation of amyloid-ß aggregates and intracellular neurofibrillary tau tangles that are characteristic of Alzheimer’s Disease.

Emerging Therapies for Alzheimer’s Disease

In this video, Dr. Sharon Cohen reviews monoclonal antibodies targeting amyloid-ß, including aducanumab, BAN-2401, solanezumab, and gantenerumab.

Interactive 3D Model of Alzheimer’s Disease Pathophysiology and Emerging Treatments

Open the model in a new window

• Use the navigation buttons in the lower-right corner of the animated 3D model to move between the 2 chapters and to play or pause the animation sequences.
• To zoom, rotate, or pan, use the CONTROLS MENU or click MORE OPTIONS > Help > 3D Navigation Basics for tips on navigating with your mouse, keyboard, or touchscreen.
• For a tutorial, click the icon for MORE OPTIONS and then select Help from the popup menu.
• To add your own drawings or notes and download your customized images, click MORE OPTIONS and then Open Whiteboard.

Impact of EDS: An Animated Tour

In this video, Dr. Bogan uses an augmented reality animation to describe the extensive impact EDS can have on both medical and psychiatric conditions.

Neurotransmitters Involved in the Sleep-Wake Cycle: An Animated Tour

In this video, Dr. Bogan uses an augmented reality animation to examine the regions of the brain that promote sleep and wakefulness, and the neurotransmitters involved.

Interaction of Stimulants with the Sleep-Wake Cycle: An Animated Tour

In this video, Dr. Bogan uses an augmented reality animation to describe the interaction of traditional stimulants such as amphetamines on the sleep-wake cycle. This video will also explain the differences between non-selective stimulants and selective stimulants such as modafinil and armodafinil.

Interaction of Solriamfetol and the Sleep-Wake Cycle: An Animated Tour

In this video, Dr. Bogan uses an augmented reality animation to explore how through the inhibition of dopamine and norepinephrine reuptake, solriamfetol produces its potent wake-promoting effect and improvement in the symptoms of EDS.

Interaction of Pitolisant and the Sleep-Wake Cycle: An Animated Tour

In this video, Dr. Bogan uses an augmented reality animation to explain how pitolisant increases levels of histamine in the brain to decrease symptoms of EDS and improve wakefulness, vigilance, attention, and memory.

NASH Pathophysiology

In this video, Dr. Mazen Noureddin uses an augmented reality animation of the human liver to describe how nonalcoholic steatohepatitis (NASH) emerges.

Molecular Targets for Emerging Therapies for NASH

In this video, Dr. Mazen Noureddin uses an augmented reality animation of the human liver to review molecules that play key roles in NASH pathophysiology and have thus been identified as targets for the development of pharmacotherapies for NASH.

An Animated Tour of the Mechanisms of HBV

In this video, Dr. Kris Kowdley uses an augmented reality animation to discuss the mechanisms involved with hepatitis B viral infection of the liver. Click the closed caption button to select subtitles in Vietnamese, Chinese (traditional), Chinese (simplified), Hmong, or Korean.

An Examination of the Stages of Fibrosis (for Clinicians)

In this video, Dr. Kris Kowdley uses an augmented reality animation to discuss the stepwise process of fibrosis progression from one stage to another. Click the closed caption button to select subtitles in Vietnamese, Chinese (traditional), Chinese (simplified), Hmong, or Korean.

The Mechanisms of HBV-Induced Hepatocellular Carcinoma

In this video, Dr. Kris Kowdley uses an augmented reality animation to discuss the primary mechanisms by which hepatitis B virus is thought to promote liver cancer. Click the closed caption button to select subtitles in Vietnamese, Chinese (traditional), Chinese (simplified), Hmong, or Korean.

An Examination of the Stages of Fibrosis (for Patients)

In this video, Dr. Kris Kowdley uses an augmented reality animation to discuss the various stages of fibrosis and the impact on the liver during each stage. Click the closed caption button to select subtitles in Vietnamese, Chinese (traditional), Chinese (simplified), Hmong, or Korean.

A Brief Overview of the Types of Hepatitis (for Patients)

In this animation, Dr. Kris Kowdley discusses the three most common viruses that cause hepatitis (hepatitis A virus, hepatitis B virus, and hepatitis C virus) and how each is transmitted. Click the closed caption button to select subtitles in Vietnamese, Chinese (traditional), Chinese (simplified), Hmong, or Korean.

An Animated Look at Addiction Pathways

Download An Animated Look at Addiction Pathways Video

An Animated Look at Acute and Chronic Pain Pathways Download the Animation Guide here (PDF)

Download Animated Look at Acute and Chronic Pain Pathways Video

Understanding Pain Pathways

Download Understanding Pain Pathways Video

An Animated Look at COPD Treatments

Take a tour of the different treatments for COPD and their impact on alveoli and at the cellular level. Represented in the animations are short-acting bronchodilators, maintenance treatment with LAMA/LABA, LABA/ICS, LAMA/LABA/ICS.

An Animated Look at COPD

In this animation, you can take an animated tour of the lungs. Click on different parts of the anatomy to better understand the animation, click to zoom in, turn, or zoom out on the structure. In Chapter 1, we begin with healthy lung that you can move around to better understand. Chapter 2 illustrates COPD with hyperinflation. Moving to Chapter 3, we see healthy alveoli, before comparing alveoli in COPD with exacerbation in Chapter 4. Finally, in Chapter 5 you can see the increase in eosinophils.

The Role of Antibody Drug Conjugates in Advanced Non-Small Cell Lung Cancer: 3D Animation

View this animation to understand the mechanisms and characteristics of antibody drug conjugates (ADCs) in NSCLC

Interactive 3D Model of Multiple Sclerosis Pathophysiology

This interactive tool contains 8 chapters detailing key aspects of the pathophysiology of multiple sclerosis that are targets for immune-directed disease-modifying therapies for MS.

• Use the navigation buttons in the lower-right corner of the animated 3D model to move between the 2 chapters and to play or pause the animation sequences.
• To zoom, rotate, or pan, use the CONTROLS MENU or click MORE OPTIONS > Help > 3D Navigation Basics for tips on navigating with your mouse, keyboard, or touchscreen.
• For a tutorial, click the icon for MORE OPTIONS and then select Help from the popup menu.
• To add your own drawings or notes and download your customized images, click MORE OPTIONS and then Open Whiteboard.

Gross Anatomy of MS

In this video, Dr. Michael Racke discusses the gross anatomy of multiple sclerosis lesions

MS Lesion Formation

In this video, Dr. Michael Racke discusses the gross anatomy of multiple sclerosis lesions

Lymphocyte Activation

In this video, Dr. Michael Racke discusses how lymphocyte activation occurs in early stages of MS.

T Cell Differentiation

In this video, Dr. Michael Racke discusses the role of T cell differentiation in the development of multiple sclerosis lesions.

Axon Demyelination

In this video, Dr. Michael Racke discusses how inflammation leads to axonal demyelination.

Remission

In this video, Dr. Michael Racke discusses what happens in the MS lesion to bring about remission.

Relapse

In this video, Dr. Michael Racke looks at how chronic inflammation can contribute to neuronal cell death and brain atrophy in progressive MS.