Post-transplant cytomegalovirus (CMV) infection afflicts as high as 80% of kidney organ transplant recipients, resulting in life-threatening direct complications, long-term negative outcomes, and significant morbidity and mortality. Current first-line antivirals administered to patients in post-treatment prophylaxis are associated with toxicity …
Rural-residing patients encounter roadblocks when they need health care. These patients likely live a considerable geographic distance from providers and facilities, the facilities themselves are far from one another, and there is a shortage of clinicians. Providers who serve in …
Recently, interleukin (IL)-23 and the inflammatory IL-23/T-helper (Th)-17 axis have been identified as central drivers of inflammation related to inflammatory bowel disease (IBD). Science in the field of cytokine-targeting therapies, specifically in the field of IL-23 P19 targeting agents, is …
The management of pain is challenging for providers, added to that the challenges of communicating with patients affected by pain in compassionate, non-stigmatizing ways that facilitate shared decision-making and individualized care. Multimodal approaches that minimize risks and maximize benefits are …
Multiple clinical practice guidelines for the treatment of endometrial cancer (EC) recommend consideration of molecular testing, particularly for high-grade tumors. Yet despite its prognostic value, molecular classification is not always a part of standard risk assessment in EC. Clinical uptake …
Familial chylomicronemia syndrome (FCS) is an autosomal recessive disorder that affects approximately 3,000 – 5,000 individuals worldwide. Though quite rare, this disorder, characterized by elevated chylomicron levels and severe hypertriglyceridemia, presents a significant challenge both for the affected patients, as …
Studies demonstrate that approximately 65%-82% of patients with Crohn’s disease (CD) report at least some degree of bowel urgency, but this symptom is largely underrecognized by gastroenterologists and health care professionals (HCPs) caring for patients with inflammatory bowel disease (IBD). …
Chronic cough, defined as a cough lasting 8 weeks or more, affects nearly 10 percent of the global adult population. More than a nuisance, chronic cough negatively impacts health-related quality-of-life and has physical, psychological, social, and financial implications due to …