Cracking the Code in PBC: Interactive Escape Room for Specialists

Faculty

Kris V. Kowdley, MD, FACP, FACG, AGAF, FAASLD
Professor, Elson S. Floyd College of Medicine
Washington State University
Spokane, WA
Director, Liver Institute Northwest
Medical Director and Senior Scientific Advisor
Velocity Clinical Research
Seattle, WA
Zobair M. Younossi, MD, MPH, FACP, FACG, AGAF, FAASLD
Chairman, Global NASH/MASH Council
Washington, DC
Professor and Chairman, Beatty Liver and Obesity Research
Inova Health System
Falls Church, VA

Statement of Need

Embark on a one-of-a-kind learning adventure designed to sharpen your diagnostic skills and treatment prowess for primary biliary cholangitis (PBC). In this immersive virtual escape room, you’ll tackle patient case challenges, uncover hidden clues, and piece together the key insights needed to crack the code to better PBC care.

Along the way, you’ll enhance your ability to recognize subtle early signs of this often-overlooked autoimmune liver disease, apply the latest evidence on disease-modifying and symptom-relieving therapies, address disparities in diagnosis and care for underserved communities, and learn practical ways to improve patient quality of life. Are you ready to think differently, diagnose earlier, and act decisively to change the course of this rare but progressive disease? Join this interactive experience informed by two world-renowned faculty experts in the field and unlock new strategies for identifying and managing PBC.

In this CME Outfitters infographic, expert faculty will implement evidence-based strategies for early and accurate diagnosis of PBC and model implementation of contemporary clinical pathways for treating PBC that address biochemical response and symptoms (e.g. pruritus, fatigue). Learners will be guided through assessment of new and emerging therapeutic pathways for PBC and their potential impact on patient outcomes.

Learning Objectives

At the conclusion of this activity, learners will be able to better:

  • Implement evidence-based strategies for early and accurate diagnosis of PBC
  • Implement contemporary clinical pathways for treating PBC that address biochemical response and symptoms (e.g. pruritus, fatigue)
  • Assess new and emerging therapeutic pathways for PBC and their potential impact on patient outcomes

 

Financial Support

This program has been supported by an independent educational grant from Gilead Sciences, Inc.

Target Audience

Hepatologists, gastroenterologists, physician associates (PAs), and nurse practitioners (NPs)

Credit Information

Jointly Accredited Provider

In support of improving patient care, CME Outfitters, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Physicians (ACCME) 1.0

CME Outfitters, LLC, designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses (ANCC) 1.0

This activity is designated for 1.00 contact hours.

California Residents: Provider approved by the California Board of Registered Nursing, Provider # CEP 15510, for 1.00 Contact Hours.

Note to Nurse Practitioners: The content of this CNE activity pertains to Pharmacology

Physician Assistants (AAPA): 1.00

CME Outfitters, LLC, has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credits. Approval is valid until 10/31/2026. PAs should only claim credit commensurate with the extent of their participation.

ABIM MOC 1.0

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

MIPS Improvement Activity

Completion of this accredited CME activity meets the expectations of an Accredited Safety or Quality Improvement Program (IA_PSPA_28) for the Merit-based Incentive Payment Program (MIPS). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

Royal College MOC

Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Kowdley reports the following financial relationships:

Consultant: 89bio, Inc.; Arbormed Pharmaceuticals; Boehringer Ingelheim; CymaBay Therapeutics Inc.; Genfit; Gilead Sciences, Inc.; GSK; HighTide Therapeutics, Inc.; Inipharm; Intercept Pharmaceuticals, Inc.; Ipsen Pharma; Madrigal Pharmaceuticals; Mirum; NGM Biopharmaceuticals; Novo Nordisk; Orphalan; Pfizer Inc.; and Zydus Pharmaceuticals, Inc.

Grants: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Research Support: 89bio, Inc.; Akero Therapeutics, Inc.; AstraZeneca; Boston Pharmaceuticals; Boehringer Ingelheim; Corcept Therapeutics, Inc.; Gilead Sciences, Inc.; GSK; Hanmi Pharmaceutical; Intercept Pharmaceuticals, Inc.; Inventiva; Janssen Pharmaceuticals, Inc.; Madrigal Pharmaceuticals; Mirum, NGM Biopharmaceuticals; Novo Nordisk; Pfizer Inc.; Pliant Therapeutics, Inc.; Terns Pharmaceuticals, Inc.; Viking Therapeutics; and Zydus Pharmaceuticals, Inc.

Speakers Bureau: AbbVie Inc.; Gilead Sciences, Inc.; Intercept Pharmaceuticals, Inc.; and Ipsen Pharma

Other financial or material support: Royalties: UpToDate

Dr. Younossi reports the following financial relationships:

Research Support/Consultant: Abbott; Akero Therapeutics, Inc.; Aligos Therapeutics; Boehringer Ingelheim; Bristol Myers Squibb Company; Cymabay Therapeutics, Inc.; GSK; Intercept Pharmaceuticals, Inc.; Ipsen Pharma; Madridgal Pharmaceuticals, Inc.; Merck & Co., Inc; Novo Nordisk; and Siemens

The following individuals have no financial relationships to disclose: 

Rebecca Vargas-Jackson, MD (Peer Reviewer)
Albert Eubanks, Jr., RN (Peer Reviewer)
Keshia Pitt, PhD (Planning Committee)
Warren Beckman (Planning Committee)
Scott J. Hershman, MD, FACEHP, CHCP (Planning Committee)
Sandra Caballero, PharmD (Planning Committee)
Sharon Tordoff (Planning Committee)

*All identified conflicts of interest have been mitigated.

Unlabeled Use Disclosure
Faculty of this CME/CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices. CME Outfitters, LLC, the faculty, planners, and reviewers do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.

Obtaining Credit

Post-tests, credit request forms, and activity evaluations must be completed online (requires free account activation), and participants can print their certificate or statement of credit immediately (70% pass rate required). This website supports all browsers except Internet Explorer for Mac.

Questions about this activity?

Call us at 877.CME.PROS (877.263.7767).

IN-013-103125-47

Cracking the Code in PBC: Interactive Escape Room for Specialists
Event Date: 10/31/2025