Breaking the Burden: Assessing and Improving Quality of Life in Patients with CRSwNP

This activity is part of a series


Joseph K. Han, MD, FARS, FAAAAI
Chief, Division of Rhinology & Endoscopic Sinus and Skull Base Surgery
Chief, Division of Allergy Eastern Virginia Medical School Norfolk, VA ARS, Immediate Past President AAAAI, RROAC, Chair
Joseph K. Han, MD, FARS, FAAAAI

Dr. Joseph Han is a Professor in the Department of Otolaryngology & Head and Neck Surgery at Eastern Virginia Medical School. He is the Chief for the Division of Rhinology & Endoscopic Sinus and Skull Base Surgery. He is also the Chief for the Division of Allergy. Previously, Dr. Han was the Director for the Division of Rhinology and Endoscopic Sinus Surgery at University of Virginia School of Medicine. Dr. Joseph Han is currently the Immediate Past President for the American Rhinologic Society. He was the President for the Virginia Society of Otolaryngology, President of the Tidewater Otolaryngology & Ophthalmology Society, President of the Korean American Otolaryngology Society, and Chair of the Rhinology and Paranasal Sinus Committee within the American Academy of Otolaryngology & Head and Neck Surgery. He is the Chair for the Rhinitis, Rhinosinusitis, and Ocular Allergy Committee within the American Academy of Allergy, Asthma, and Immunology.

Dr. Han was an Associate Editor and is on the Editorial Board for the International Forum of Allergy and Rhinology. Dr. Han is currently a guest examiner for the American Board of Otolaryngology & Head and Neck Surgery. Dr. Han is the Editor for the book Practical Medical and Surgical Management of Chronic Rhinosinusitis and Rhinology Section Editor for the Ballenger’s Otolaryngology Head and Neck Surgery. He has over 118 scientific publications, over 157 national and international scientific presentations, and over 148 guest lectureships.

Dr. Han is a fellow of the American Academy of Otolaryngology & Head and Neck Surgery (AAO-HNS), American Rhinologic Society (ARS), Triological Society, American Academy of Allergy, Asthma, and Immunology (AAAAI), American College of Surgeons (ACS), and American Academy of Otolaryngic Allergy (AAOA). He was involved in the Guideline Task Force. Dr. Han is one of the few physicians who is a fellow of the ARS, AAAAI, and AAOA. Dr. Han has received numerous awards including Best Doctors of America and Top Doctors by US News & Report.

Dr. Han is very active in both basic science research as well as clinical research studies. His thesis was on subclassification of CRS, which is endotyping and phenotyping CRS. He has been awarded NIH funding for the study of chronic sinusitis and has been the lead investigators for several multi-national, multi- institutional, prospective clinical trials on chronic sinusitis and nasal polyposis.

Stella Lee, MD
Section Chief, Rhinology
Division of Otolaryngology-Head & Neck Surgery
Brigham and Women's Hospital Harvard Medical School Boston, MA
Stella Lee, MD

Dr. Stella Lee is a fellowship-trained rhinologist and director of the Brigham Sinus Center. She is a clinician scientist developing novel management strategies for the care of patients with inflammatory upper airway disease as well as a leader in the development of therapeutics for airway inflammation. Her philosophy is to provide multi-disciplinary care with experts in the field for the best outcome possible for her patients.

Dr. Lee earned her Bachelor of Science degree in Neuroscience from Duke University before attending the Chicago Medical School. She completed her residency in Otolaryngology-Head and Neck Surgery at Yale University, followed by a fellowship in Rhinology and Skull Base Surgery at Johns Hopkins University. Before joining the Brigham faculty, Dr. Lee served as the Division Chief for Sinonasal Disorders and Allergy in the Department of Otolaryngology at the University of Pittsburgh Medical Center for ten years.

Her research interests include understanding the inflammatory endotypes of chronic rhinosinusitis, the impact of environmental pollution on airway inflammation, and development of basic to translational approaches to solve chronic inflammation ( She is a leader in the investigation of targeted therapeutics and creation of new paradigms of how we conceptualize and treat upper airway disorders.

Statement of Need

Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a chronic inflammatory disease characterized by rhinosinusitis and the development of polyposis originating in the sinus and eventually extending to the nose. Persistent symptoms include congestion, stuffiness, nasal discharge, facial pain and/or pressure, impairment, or loss of sense of smell, and fatigue. CRSwNP confers a substantial but often underappreciated burden, negatively impacting mental and physical health-related quality of life (HRQoL) endpoints. To help alleviate this burden clinicians need to recognize the impact of CRSwNP and its many comorbidities on patients’ HRQoL and understand how the severity of CRSwNP can affect treatment response and duration.

In part one of this CMEO Snack series on CRSwNP, join Dr. Han and Dr. Lee as they discuss strategies for how clinicians can better recognize and understand the impact of the burden posed by CRSwNP.

Learning Objectives

At the end of this CME/CE activity, participants should be able to recognize the burden of CRSwNP and the impact of this disease on patients’ HRQoL and treatment response.

Financial Support

This activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc. and Sanofi Genzyme.

Target Audience

Physicians, PAs, nurse practitioners, nurses and pharmacists specializing in allergy/immunology, and otolaryngology practicing globally.

Credit Information

Jointly Accredited Provider

In support of improving patient care, CME Outfitters, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physicians (ACCME) 0.5

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Pharmacists/Pharmacy Tech (ACPE) 0.5

This application-based activity is approved for 0.5 contact hours (0.05 CEUs) of continuing pharmacy credit.
Activity UAN: 0376-0000-21-062-H02-P

Nurses (ANCC) 0.5

This activity is designated for 0.5 contact hours.

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MIPS Improvement Activity

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Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Han reports the following financial relationships: Research Support: AstraZeneca; Genentech, Inc.; GlaxoSmithKline; Novartis Pharmaceuticals Corporation; Regeneron Pharmaceuticals, Inc.; and Sanofi Genzyme

Dr. Lee reports the following financial relationships: Consultant and Research Support: AstraZeneca; Genentech, Inc.; Novartis Pharmaceuticals Corporation; GlaxoSmithKline; and Sanofi Regeneron

  • Shirley Michelle Franks, MSN, APRN, FNP-BC (peer reviewer)
  • Janan Sarwar, PharmD (planning committee)
  • Evan Luberger (planning committee)
  • Susan H. Yarbrough, CHCP (planning committee)
  • Sharon Tordoff (planning committee)

Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

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NOTE: Pharmacist CE Universal Activity Number, Enduring: 0376-0000-21-062-H02-P.

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Breaking the Burden: Assessing and Improving Quality of Life in Patients with CRSwNP
Event Date: 04/22/2022