Between the Lines: What the Guidelines Say about Current Therapies for Patients with CRSwNP

This activity is part of a series

Faculty

Joseph K. Han, MD, FARS, FAAAAI
Professor
Chief, Division of Rhinology & Endoscopic Sinus and Skull Base Surgery
Chief, Division of Allergy Eastern Virginia Medical School Norfolk, VA ARS, Immediate Past President AAAAI, RROAC, Chair
Joseph K. Han, MD, FARS, FAAAAI

Dr. Joseph Han is a Professor in the Department of Otolaryngology & Head and Neck Surgery at Eastern Virginia Medical School. He is the Chief for the Division of Rhinology & Endoscopic Sinus and Skull Base Surgery. He is also the Chief for the Division of Allergy. Previously, Dr. Han was the Director for the Division of Rhinology and Endoscopic Sinus Surgery at University of Virginia School of Medicine. Dr. Joseph Han is currently the Immediate Past President for the American Rhinologic Society. He was the President for the Virginia Society of Otolaryngology, President of the Tidewater Otolaryngology & Ophthalmology Society, President of the Korean American Otolaryngology Society, and Chair of the Rhinology and Paranasal Sinus Committee within the American Academy of Otolaryngology & Head and Neck Surgery. He is the Chair for the Rhinitis, Rhinosinusitis, and Ocular Allergy Committee within the American Academy of Allergy, Asthma, and Immunology.

Dr. Han was an Associate Editor and is on the Editorial Board for the International Forum of Allergy and Rhinology. Dr. Han is currently a guest examiner for the American Board of Otolaryngology & Head and Neck Surgery. Dr. Han is the Editor for the book Practical Medical and Surgical Management of Chronic Rhinosinusitis and Rhinology Section Editor for the Ballenger’s Otolaryngology Head and Neck Surgery. He has over 118 scientific publications, over 157 national and international scientific presentations, and over 148 guest lectureships.

Dr. Han is a fellow of the American Academy of Otolaryngology & Head and Neck Surgery (AAO-HNS), American Rhinologic Society (ARS), Triological Society, American Academy of Allergy, Asthma, and Immunology (AAAAI), American College of Surgeons (ACS), and American Academy of Otolaryngic Allergy (AAOA). He was involved in the Guideline Task Force. Dr. Han is one of the few physicians who is a fellow of the ARS, AAAAI, and AAOA. Dr. Han has received numerous awards including Best Doctors of America and Top Doctors by US News & Report.

Dr. Han is very active in both basic science research as well as clinical research studies. His thesis was on subclassification of CRS, which is endotyping and phenotyping CRS. He has been awarded NIH funding for the study of chronic sinusitis and has been the lead investigators for several multi-national, multi- institutional, prospective clinical trials on chronic sinusitis and nasal polyposis.

Claire Hopkins, MA, FRCS, DM
Consultant ENT Surgeon Guy's Hospital
Professor of Rhinology King's College London, UK
Claire Hopkins, MA, FRCS, DM

Claire Hopkins, MA, FRCS, DM is a Consultant Rhinologist at Guy’s Hospital, a large tertiary referral center in London, UK, with a clinical practice covering the breadth of rhinology including sinusitis, anterior skull base work, and facial plastics. She is a Professor at King’s College London. She is the Past-President of the British Rhinological Society, Academic Chair of ENTUK/BACO and the President elect of the Royal Society of Medicine’s Section of Laryngology and Rhinology. Dr. Hopkins is co-author of the European Position Statement on Rhinosinusitis and Nasal Polyps and the International Consensus on Rhinosinusitis. She has a large research program covering all aspects of medical and surgical management of rhinitis and sinus disease, with a focus on improving outcomes in the management of nasal polyps.

Statement of Need

Clinicians may be familiar with current guideline recommendations for the use of traditional CRSwNP therapies (e.g., corticosteroids, sinosurgery). However, new global guidance has been issued from EUFOREA for use of biologics in the management of uncontrolled CRSwNP. These guidelines include a practical algorithm to define type 2 inflammation in order to enable an informed and shared decision-making process for the selection of biologic agents. Additionally, both general and specialist HCPs report uncertainty and variability regarding the best management of chronic rhinosinusitis.

In part 2 of this CMEO Snack series, join Dr. Han and Dr. Hopkins as they translate the updated guideline recommendations and discuss how to implement the suggestions into clinically meaningful changes in practice. Translation of the guidance by experts in the field will assist in a better understanding and application of the guidance to clinical practice.

Learning Objectives

At the end of this CME/CE activity, participants should be able to:

Translate updated guideline recommendations to treatment decisions for the management of uncontrolled CRSwNP.

Financial Support

This activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc. and Sanofi Genzyme.

Target Audience

Physicians, PAs, nurse practitioners, nurses, and pharmacists specializing in allergy/immunology, and otolaryngology practicing globally.

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Dr. Han reports the following financial relationships: Research Support: AstraZeneca; Genentech, Inc.; GlaxoSmithKline; Novartis Pharmaceuticals Corporation; Regeneron Pharmaceuticals, Inc.; and Sanofi Genzyme


Dr. Han reports the following financial relationships: Research Support: AstraZeneca; Genentech, Inc.; GlaxoSmithKline; Novartis Pharmaceuticals Corporation; Regeneron Pharmaceuticals, Inc.; and Sanofi Genzyme


Dr. Hopkins reports the following financial relationships: Advisory Board: GlaxoSmithKline. Consultant: AstraZeneca and Sanofi Genzyme. Speakers Bureau: Intersect ENT, Inc.; Mylan Pharmaceuticals, Inc.; and Olympus Corporation


Shirley Michelle Franks, MSN, APRN, FNP-BC (peer reviewer)

Janan Sarwar, PharmD (planning committee)

Evan Luberger (planning committee)

Susan H. Yarbrough, CHCP (planning committee)

Sharon Tordoff (planning committee)

Disclosures were obtained from the CME Outfitters, LLC staff: No disclosures to report.


Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

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NOTE: Pharmacist CE Universal Activity Number, Enduring: JA0007185-0000-22-059-H01-P.

 

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SN-162-042222-90

Between the Lines: What the Guidelines Say about Current Therapies for Patients with CRSwNP
Event Date: 04/22/2022