2025 Conference Coverage: Optimizing the Holistic Health of Patients with Narcolepsy and IH: Meetings to Make Heart and Health Connections

Faculty

Richard K. Bogan, MD, FCCP, FAASM
Associate Clinical Professor
University of South Carolina School of Medicine
Principal, Bogan Sleep Consultants, LLC
Columbia, SC
Anne Marie Morse, DO, FAASM
Moderator
Director, Child Neurology
Director, Pediatric Sleep Medicine
Program Director, Child Neurology Residency
Geisinger Janet Weis Children's Hospital
Associate Professor, Geisinger Commonwealth School of Medicine
School of Medicine
Danville, PA

Statement of Need

Idiopathic hypersomnia (IH) and narcolepsy diagnoses share similar symptoms and comorbidities, including cardiovascular (CV), cardiometabolic (CM), neurologic, and psychiatric conditions. Healthcare professionals (HCPs) with patients who have IH or narcolepsy and one or more of these comorbidities need to recognize the cumulative impact that these overlapping conditions have on their patients’ quality of life (QoL) and tailor the approach to treatment accordingly.

The resulting individualized treatment plan can include working within a multidisciplinary, interprofessional team of caregivers, utilizing a holistic and interdisciplinary treatment strategy that manages the neurological, psychiatric, and cardiovascular risks for these patients. Treatment decisions should consider efficacy, safety, patient preference, and the cumulative burden of lifelong therapy.

In this CMEO Journal Club, expert faculty will present and discuss the very latest research abstracts from the American Academy of Neurology (AAN) 2025 Annual Meeting and the Associated Professional Sleep Societies (APSS) SLEEP 2025 Annual Meeting, including the latest information on psychiatric and CV/CM comorbidities for patients living with IH and narcolepsy, the impact of these comorbidities on patients’ QoL, and how to customize treatment that mitigates risk.

Learning Objectives

At the conclusion of this activity, learners will be able to better:

  • Identify the prevalence of psychiatric and CV/CM comorbidities associated with IH and narcolepsy
  • Evaluate the clinical and quality of life (QoL) impacts of psychiatric and CV/CM comorbidities on patients living with IH and narcolepsy
  • Tailor treatment selection for narcolepsy or IH that mitigates risk for CV/CM disease or its exacerbation, with a focus on the importance of sodium intake

Financial Support

This program is supported by an independent medical education grant from Jazz Pharmaceuticals.

Target Audience

Neurologists, cardiologists, and the care team members including physician associates (PAs), nurse practitioners (NPs), nurses, and pharmacists

Credit Information

Jointly Accredited Provider

In support of improving patient care, CME Outfitters, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Physicians (ACCME) 1.0

CME Outfitters, LLC, designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Pharmacists (ACPE) 1.0

This application-based activity is approved for 1.00 contact hours (0.1 CEUs) of continuing pharmacy credit (JA0007185-0000-25-055-H01-P).

Nurses (ANCC) 1.0

This activity is designated for 1.00 contact hours.

California Residents: Provider approved by the California Board of Registered Nursing, Provider # CEP 15510, for 1.00 Contact Hours.

Physician Assistants (AAPA): 1.00

CME Outfitters, LLC, has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credits. Approval is valid until 07/02/2026. PAs should only claim credit commensurate with the extent of their participation.

ABIM MOC 1.0

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

MIPS Improvement Activity

Completion of this accredited CME activity meets the expectations of an Accredited Safety or Quality Improvement Program (IA_PSPA_28) for the Merit-based Incentive Payment Program (MIPS). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

Royal College MOC

Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Bogan reports the following financial relationships:

Consultant: Alkermes; Apnimed, Inc.; Avadel; Daiichi Sankyo, Inc.; Eisai Inc.; Harmony Biosciences; and Takeda Pharmaceutical Company Limited

Research Support: Apnimed, Inc.; AstraZeneca; Avadel; Axsome Therapeutics, Inc.; Balance; Bayer; Bresotec Medical; Centessa Pharmaceuticals; Eisai Inc.; Fisher & Paykel Healthcare Limited; Fresca Medical, Inc.; Idorsia Pharmaceuticals; Insilico Medicine; Jazz Pharmaceuticals, Inc.; LivaNova; Merck & Co., Inc.; Mineralys Therapeutics, Inc.; NLS Pharmaceutics; Noctrix; Oura; Philips; Rho, Inc.; Roche; Sanofi; Sommetrics, Inc.; Suven Life Sciences; Takeda Pharmaceutical Company Limited; Zevra Therapeutics; and ZiO Health Ltd

Speakers Bureau for Axsome Therapeutics, Inc.; Eisai Inc.; Harmony Biosciences; Idorsia Pharmaceuticals; and Jazz Pharmaceuticals, Inc.

Shareholder: Healthy Humming, LLC and Watermark Medical

Board of Directors: Watermark Medical

Dr. Morse reports the following financial relationships:

Advisory Board: Alkermes; Apnimed, Inc.; Avadel; FloraWorks; Jazz Pharmaceuticals, Inc.; Pulse Infoframe, Inc.; and Neura Health

Consultant: Alkermes; Apnimed, Inc.; Avadel; Harmony Biosciences; Jazz Pharmaceuticals, Inc.; and Takeda Pharmaceutical Company

Grants: Harmony Biosciences and Resmed

Research Support: Avadel; Jazz Pharmaceuticals, Inc.; National Institutes of Health (NIH); Takeda Pharmaceutical Company; and UCB, Inc.

Speakers Bureau: Avadel; Harmony Biosciences; and Lilly

Stock Shareholder (ownership interest): Floraworks (SAB)

Other financial or material support: UpToDate and Forbes

The following individuals have no financial relationships to disclose:

Rebecca Vargas-Jackson, MD (Peer Reviewer)
Michael Franks, APRN, AGACNP-BC, FNP-BC (Peer Reviewer)
Mary Gleason, PhD, CHCP (Planning Committee)
Felicia Oyedepo, MD (Planning Committee)
Scott J. Hershman, MD, FACEHP, CHCP (Planning Committee)
Sandra Caballero, PharmD (Planning Committee)
Sharon Tordoff (Planning Committee)

 

*All identified conflicts of interest have been mitigated.

Unlabeled Use Disclosure
Faculty of this CME/CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices. CME Outfitters, LLC, the faculty, planners, and reviewers do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.

Questions about this activity?

Call us at 877.CME.PROS (877.263.7767).

JC-032-070225-43

2025 Conference Coverage: Optimizing the Holistic Health of Patients with Narcolepsy and IH: Meetings to Make Heart and Health Connections
Event Date: 07/02/2025