FB-001 Post Test Step 1 of 2 50% Name* First Last Email* Retinitis pigmentosa usually affects which cell type first?*A. ConesB. RodsC. RPED. None of the aboveStargardt disease:*A. Only affects adultsB. Is caused by mutations in RPE65C. Is caused by buildup of toxins in RPE cellsD. Can be caused by one of seven genesAntisense oligonucleotides are used in:*A. RNA therapiesB. Gene augmentation/replacementC. Anti-VEGF injectionsD. None of the aboveGene augmentation/replacement trials are underway for:*A. Retinitis pigmentosaB. ChoroideremiaC. People with mutations in RPGRD. All of the aboveAchromatopsia is a condition that causes:*A. Extreme light sensitivityB. Hearing lossC. Corneal abrasionsD. Night blindnessA central scotoma is the hallmark of:*A. Retinitis pigmentosaB. Stargardt diseaseC. ChoroideremiaD. Usher syndromePatients registries for IRDs:*A. Always protect a patients’ privacyB. Help patients get on the radar of researchers and companiesC. Are monitored by the FDAD. Limit the number of registrantsEmerging stem cell therapies for IRDs:*A. Can be designed to protect existing retinal cellsB. Can be designed to replace lost retinal cellsC. Are only injected subretinallyD. a. and/or b.Usher syndrome is:*A. Always inherited recessivelyB. A leading cause of combined hearing and vision lossC. Not easy to diagnose through genetic testingD. a. and b.10) Which of the following are true?*A. Genetic testing provides a conclusive result in 60-70% of IRD casesB. If a patient has an IRD, it is almost certain one of their relatives has the conditionC. Diabetes increases the risk of an IRDD. a. and c.