Navigating Prevention: A Stepwise Guide to PrEP and Sexual Health Discussions

Statement of Need

Despite national recommendations, PrEP remains underutilized in many clinical settings because clinicians often lack confidence, time, and practical workflows to consistently identify candidates and act on eligibility findings. Routine care frequently omits a structured sexual health history and assessment, leading to missed opportunities to recognize patients who could benefit from PrEP, while uncertainty about which clinical, behavioral, and demographic factors should prompt initiation contributes to inconsistent decision-making and inequitable access. An interactive CME activity is needed to help clinicians integrate guideline-recommended PrEP eligibility evaluations into everyday practice—normalizing concise, patient-centered sexual health history-taking and assessment—and to strengthen skills in selecting appropriate individuals for PrEP initiation so that eligible patients are identified earlier, counseled effectively, and started on PrEP promptly and appropriately.

This CME Outfitters program will incorporate an interactive decision-tree tool to help clinicians apply evidence-based strategies in real time. Decision trees transform complex guidelines into practical, case-based pathways that clarify when to adjust therapy and integrate emerging treatments. By engaging clinicians in realistic scenarios, this format addresses integrating guideline-recommended evaluations for PrEP eligibility, as well as Strategies for selecting appropriate individuals for PrEP initiation.

Learning Objectives

At the conclusion of this activity, learners will be able to better:

Integrate guideline-recommended evaluations for PrEP eligibility in practice including a sexual health history and risk assessment
Select appropriate individuals for PrEP initiation

Financial Support

This program has been supported by an independent educational grant from Gilead Sciences, Inc.

Target Audience

Primary care providers (PCPs), internists, nurse practitioners (NPs), physician associates (PAs), nurses, and pharmacists

Credit Information

Jointly Accredited Provider

In support of improving patient care, CME Outfitters, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Physicians (ACCME) 0.5

CME Outfitters, LLC, designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Pharmacists (ACPE) 0.5

This application-based activity is approved for 0.50 contact hours (0.05 CEUs) of continuing pharmacy credit (JA0007185-0000-26-058-H99-P).

Nurses (ANCC) 0.5

This activity is designated for 0.50 contact hours.

California Residents: Provider approved by the California Board of Registered Nursing, Provider # CEP 15510, for 0.50 Contact Hours.

Physician Associates (AAPA): 0.5

CME Outfitters, LLC, has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 0.50 AAPA Category 1 CME credits. Approval is valid until 06/02/2027. PAs should only claim credit commensurate with the extent of their participation.

ABIM MOC 0.5

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

MIPS Improvement Activity

Completion of this accredited CME activity meets the expectations of an Accredited Safety or Quality Improvement Program (IA_PSPA_28) for the Merit-based Incentive Payment Program (MIPS). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

Royal College MOC

Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Wohl reports the following financial relationships:

Advisory Board: Gilead Sciences, Inc.; Merck & Co., Inc.; and ViiV Healthcare

Grants and Research Support to UNC: Gilead Sciences, Inc.; Merck & Co., Inc.; and ViiV Healthcare

The following individuals have no financial relationships to disclose:

Rebecca Vargas-Jackson, MD (Peer Reviewer)
Albert Eubanks, Jr., RN (Peer Reviewer)
Thomas Mitchell, MSW, LSW (Planning Committee)
Evan Luberger (Planning Committee)
Kashemi D. Rorie, PhD (Planning Committee)
Estelle Perera (Planning Committee)
Sandra Caballero, PharmD (Planning Committee)
Sharon Tordoff (Planning Committee)

*All identified conflicts of interest have been mitigated.

Unlabeled Use Disclosure
Faculty of this CME/CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices. CME Outfitters, LLC, the faculty, planners, and reviewers do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.

Obtaining Credit

Post-tests, credit request forms, and activity evaluations must be completed online (requires free account activation), and participants can print their certificate or statement of credit immediately (70% pass rate required). This website supports all browsers except Internet Explorer for Mac.

Questions about this activity?

Call us at 877.CME.PROS (877.263.7767).

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