Activity Details (PDF Format)
	Course Materials (PDF Format)
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	Participate in On Demand Activity
	Complete Post-Test/ Print CE Certificate
	Faculty
	Statement of Need
	Activity Goal
	Learning Objectives
	Target Audience
	Financial Support
	Credit Information

Premiere Date: Tuesday, June 20, 2006
Live Audioconference Series (15 sessions): June - August, 2006

This activity offers CE credit for:

1. Physicians (ACCME/AMA PRA Category 1)
2. Nurses (CNE)
3. Pharmacists (ACPE)
4. Psychologists (APA)
5. Social Workers (NASW)
6. Certified Case Managers (CCMC)

All other clinicians will either receive a CME Attendance Certificate or may choose any of the types of CE credit being offered.
Credit Expiration Date:
Tuesday, August 21, 2007

Faculty

Charles B. Nemeroff, MD, PhD Reunette W. Harris Professor Department of Psychiatry and Behavioral Sciences Emory University School of Medicine Atlanta, GA

Alan F. Schatzberg, MD Kenneth T. Norris, Jr. Professor and Chairman of the Department of Psychiatry and Behavioral Sciences Stanford University School of Medicine Stanford, CA

Faculty Bios and Disclosure Declaration

All faculty participating in CME Outfitters continuing education activities are required to disclose any conflict(s) of interest related to the content of their presentation(s) as defined by the ACCME's Standards for Commercial Support, and other accrediting and regulatory bodies. Full disclosure of faculty relationships will be made prior to registration availability for this activity on this website and within the activity syllabus/course guide.

Statement of Need

Depression with atypical features is characterized by mood reactivity in conjunction with any two of the following - hypersomnia, leaden paralysis, hyperphagia, and interpersonal rejection sensitivity. Some data show that patients with depression with atypical features experience greater functional impairment than their non-atypical counterparts, as well as exhibiting more interpersonal sensitivity, more chronic dysphoria, and more bipolar II disorder.(1) There is some uncertainty regarding how to best characterize patients with depression with atypical features because patients with bipolar disorder, anxious depression, and personality disorder all share similar presentations.(2) Over the years, treatment of depression with atypical features has ranged from monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, selective serotonin reuptake inhibitors, bupropion, venlafaxine, and cognitive behavioral therapy.(3) Emerging data demonstrate that newer delivery systems may provide a statistically significant and improved antidepressant benefit.(4) In this first of a two-part evidence-based and interactive CME Outfitters/psychCME TALK series, the experts will help clinicians to recognize, diagnose, and manage depression with atypical features.

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1. Agosti V, Stewart JW. Atypical and non-atypical subtypes of depression: comparison of social functioning, symptoms, course of illness, co-morbidity and demographic features. J Affect Disord 2001 Jun;65(1):75-9.
2. Nierenberg AA, Alpert JE, Pava J, Rosenbaum JF, Fava M. Course and treatment of atypical depression. J Clin Psychiatry 1998;59 (Suppl 18):5-9.
3. Liebowitz MR, et al. Antidepressant specificity in atypical depression. Arch Gen Psychiatry 1988;45:129-37.
4. Amsterdam J. A double-blind, placebo-controlled trial of the safety and efficacy of selegiline transdermal system without dietary restrictions in patients with major depressive disorder. J Clin Psychiatry 2003;64:208-214.

Activity Goal

To provide evidence-based educational information and clinical context regarding the efficacy of medications used in the treatment of depression with atypical features.

Learning Objectives

At the end of this CE activity, participants should be able to:

• Differentiate the unique symptomatology of depression with atypical features from other depressive disorders.
• Compare and contrast the receptor profiles of various treatment options for patients with depression with atypical features.
• Evaluate the strength of evidence for novel treatments and delivery systems in patients with depression with atypical features.

Target Audience

Physicians, physician assistants, nurse practitioners, nurses, psychologists, social workers, certified case managers, pharmacists, and other healthcare professionals with an interest in mental health.

Financial Support

CME Outfitters, LLC, gratefully acknowledges an educational grant from Bristol-Myers Squibb Company in support of this CE activity.

Credit Information

CME Credit (Physicians):
CME Outfitters, LLC, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. CME Outfitters, LLC, designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Note to Physician Assistants: AAPA accepts Category I credit from AOACCME, Prescribed credit from AAFP, and AMA Category I CME credit for the PRA from organizations accredited by ACCME.

CNE Credit (Nurses):
This Educational Activity is presented by CME Outfitters, LLC, which has been approved as a provider of continuing education by the New York State Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation.

It has been assigned code 5UYSJZ-PRV-0496. 1.0 contact hour (Pharmacology)

CEP Credit (Psychologists):
CME Outfitters is approved by the American Psychological Association to sponsor continuing education for psychologists. CME Outfitters maintains responsibility for this program and its content. (1.0 CE credits)

NASW Credit (Social Workers):
This program was approved by the National Association of Social Workers (provider #886407722) for 1 continuing education contact hour.

CCMC Credit (Certified Case Managers):
This program has been approved for 1 hour by the Commission for Case Manager Certification (CCMC).

CPE Credit (Pharmacists):
CME Outfitters, LLC, is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. 1.0 contact hours (0.1 CEUs)
Universal Program Number: 376-999-06-012-L01 (live interactive session) 376-999-06-012-H01 (recorded activities)

To receive credit, participants must review all activity materials in their entirety, score 70% or above on a post-test, and fully complete and return both the credit request form and activity evaluation. A certificate or statement of credit will be mailed within 4-6 weeks to all who successfully complete these requirements.

Questions about this CE activity? Call us at 877.CME.PROS (877.263.7767).

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